Evidence map›Paper›PMID 32929504›Full record

ArticleSleep2021

Natural history of insomnia symptoms in the transition from childhood to adolescence: population rates, health disparities, and risk factors.

Julio Fernandez-Mendoza, Elizaveta Bourchtein, Susan Calhoun, Kristina Puzino, Cynthia K Snyder, Fan He, Alexandros N Vgontzas, Duanping Liao, Edward Bixler

Open access · bronzeAbstract read
In one paragraph

Article in Sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Guideline
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  10. Observational
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  13. Weighted blankets used in pediatric sleep treatment in attention-deficit/hyperactivity disorder and childhood maltreatment: where are we now and where are we going?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  14. Article
  15. Article
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  18. Edward O. Bixler, PhD: from the Apollo project and chimpanzees to sleep epidemiology.Sleep advances : a journal of the Sleep Research Society · 2024
    Article
  19. Article
  20. The association between sleep quality and obstructive sleep apnea with health-related quality of life in children with obesity.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Julio Fernandez-MendozaSleep Research & Treatment Center, Department of Psychiatry and Behavioral Health, Penn State Health Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, PA.
Elizaveta BourchteinSleep Research & Treatment Center, Department of Psychiatry and Behavioral Health, Penn State Health Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, PA.
Susan CalhounSleep Research & Treatment Center, Department of Psychiatry and Behavioral Health, Penn State Health Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, PA.
Kristina PuzinoSleep Research & Treatment Center, Department of Psychiatry and Behavioral Health, Penn State Health Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, PA.
Cynthia K SnyderDepartment of Pediatrics, Penn State Health Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, PA.
Fan HeDepartment of Public Health Sciences, Penn State Health Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, PA.
Alexandros N VgontzasSleep Research & Treatment Center, Department of Psychiatry and Behavioral Health, Penn State Health Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, PA.
Duanping LiaoDepartment of Public Health Sciences, Penn State Health Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, PA.
Edward BixlerSleep Research & Treatment Center, Department of Psychiatry and Behavioral Health, Penn State Health Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, PA.
Penn State Milton S. Hershey Medical Center · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
The Penn State Child Sleep Cohort: Cardiometabolic and Neurocognitive Risk in Young AdulthoodR01HL136587 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI FERNANDEZ-MENDOZA, JULIO · 2018 to 2022
$3.7M
Sleep and cardio-metabolic risk factors: a prospective study of adolescentsR01HL097165 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BIXLER, EDWARD O., LIAO, DUANPING · 2010 to 2013
$2.2M
PREVALENCE OF SLEEP DISORDERED BREATHING IN CHILDRENR01HL063772 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BIXLER, EDWARD O. · 2001 to 2005
$1.3M
Sleep Cortical Dynamics and Neurobehavioral Risk in Children and Adolescents: A Longitudinal StudyR01MH118308 · NIMH · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI FERNANDEZ-MENDOZA, JULIO · 2019 to 2021
$1.2M
NCATS NIH HHS UL1 TR000127NHLBI NIH HHS R01 HL063772NHLBI NIH HHS R01 HL097165NHLBI NIH HHS R01 HL136587NIMH NIH HHS R01 MH118308
6 · The paper itself

Abstract

STUDY

objectivesTo determine the sociodemographic, behavioral, and clinical risk factors associated with the persistence, remission, and incidence of insomnia symptoms in the transition from childhood to adolescence.

methodsThe Penn State Child Cohort is a random, population-based sample of 700 children (5-12 years at baseline), of whom 421 were followed-up as adolescents (12-23 years at follow-up). Subjects underwent polysomnography, clinical history, physical exam, and parent- and self-reported scales at baseline and follow-up. Insomnia symptoms were defined as a parent- or self-report of difficulty falling and/or staying asleep.

resultsThe 421 subjects with baseline (Mage = 8.8 years) and follow-up (Mage = 17 years) data were 53.9% male and 21.9% racial/ethnic minorities. The persistence of childhood insomnia symptoms (CIS) was 56% (95% CI = 46.5-65.4), with only 30.3% (95% CI = 21.5-39.0) fully remitting. The incidence of adolescent insomnia symptoms was 31.1% (95% CI = 25.9-36.3). Female sex, racial/ethnic minority, and low socioeconomic status as well as psychiatric/behavioral or neurological disorders, obesity, smoking, and evening chronotype were associated with a higher persistence or incidence of insomnia symptoms.

conclusionsCIS are highly persistent, with full remission occurring in only a third of children in the transition to adolescence. Sex-, racial/ethnic-, and socioeconomic-related disparities in insomnia occur as early as childhood, while different mental/physical health and lifestyle/circadian risk factors play a key role in the chronicity of CIS versus their incidence in adolescence. CIS should not be expected to developmentally remit and should become a focus of integrated pediatric/behavioral health strategies.

Indexed as

Sleep Initiation and Maintenance DisordersAdolescentChildEthnicityFemaleHumansMaleMental HealthMinority GroupsRisk Factorsepidemiologyinsomnialongitudinalpediatrics

Identifiers

PMID32929504
PMCPMC7953218
OpenAlexW3087044206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.