Evidence map›Paper›PMID 32929395›Full record

ArticleAmerican journal of nuclear medicine and molecular imaging2020

Altered splenic [

Human Adams, Bob Meek, Ewoudt Mw van de Garde, Coline Hm van Moorsel, Danielle J Vugts, Ruth G Keijsers, Jan C Grutters

Abstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. QuantitativeArthritis research & therapy · 2024
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Human AdamsDepartment of Pulmonology, ILD Center of Excellence, St. Antonius Hospital Nieuwegein, The Netherlands.
Bob MeekDepartment of Medical Microbiology & Immunology, St Antonius Hospital Nieuwegein, The Netherlands.
Ewoudt Mw van de GardeDepartment of Clinical Pharmacy, St Antonius Hospital Nieuwegein, The Netherlands.
Coline Hm van MoorselDepartment of Pulmonology, ILD Center of Excellence, St. Antonius Hospital Nieuwegein, The Netherlands.
Danielle J VugtsDepartment of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands Radiology and Nuclear Medicine, VU Medical Center, Amsterdam, The Netherlands Radiology and Nuclear Medicine, VU Medical Center Amsterdam, The Netherlands.
Ruth G KeijsersDepartment of Nuclear Medicine, St Antonius Hospital Nieuwegein, The Netherlands.
Jan C GruttersDepartment of Pulmonology, ILD Center of Excellence, St. Antonius Hospital Nieuwegein, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rituximab (RTX) for immune-mediated inflammatory disease (IMID) with interstitial pneumonitis (IP) results in non-response in about a third of patients for reasons not well understood. Complete peripheral B-cell depletion in IMID-IP does not seem to correlate with successful treatment outcome. A hypothesis is that splenic B cells might play a role in B-cell recovery and attraction of naïve B cells in non-responsive patients. The aim of this post hoc analysis of clinical trial data is to search for indicators in [

Indexed as

[89Zr]Zr-rituximabCD20 cellsclinical researchimmunologyinterstitial lung diseasePET/CTrituximabSpleen

Identifiers

PMID32929395
PMCPMC7486548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.