Evidence map›Paper›PMID 32929375›Full record

ArticleTheranostics2020

Melatonin overcomes MCR-mediated colistin resistance in Gram-negative pathogens.

Yuan Liu, Yuqian Jia, Kangni Yang, Ziwen Tong, Jingru Shi, Ruichao Li, Xia Xiao, Wenkai Ren, Rüdiger Hardeland, Russel J Reiter and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Repurposing loratadine to reverse colistin resistance inEmerging microbes & infections · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Discovery of HAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. α-Terpineol reversesFrontiers in cellular and infection microbiology · 2026
    Article
  14. PFK-158 enhances colistin efficacy against resistantFrontiers in veterinary science · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Yuan LiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.
Yuqian JiaCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.
Kangni YangCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.
Ziwen TongCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.
Jingru ShiCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.
Ruichao LiCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.
Xia XiaoCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.
Wenkai RenState key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Laboratory of Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Rüdiger HardelandJohann Friedrich Blumenbach Institute of Zoology and Anthropology, University of Göttingen, 37073 Göttingen, Germany.
Russel J ReiterDepartment of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, 78229 TX, USA.
Zhiqiang WangCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.
Yangzhou University · CNUniversity of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Bacterial AgentsBacterial Outer MembraneCell Membrane PermeabilityColistinDisease Models, AnimalDrug Resistance, BacterialDrug SynergismDrug Therapy, CombinationEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsFemaleHumansMelatoninMiceAnti-Bacterial AgentsColistinEscherichia coli ProteinsMCR-1 protein, E coliMelatoninantibiotic adjuvantbacterial infectionscolistingram-negative pathogenmelatonin

Identifiers

PMID32929375
PMCPMC7482817
OpenAlexW3083935039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.