Evidence map›Paper›PMID 32929364›Full record

Observational studyTheranostics2020

Dissecting the heterogeneity of the alternative polyadenylation profiles in triple-negative breast cancers.

Lei Wang, Guan-Tian Lang, Meng-Zhu Xue, Liu Yang, Li Chen, Ling Yao, Xiao-Guang Li, Peng Wang, Xin Hu, Zhi-Ming Shao

Abstract readObservational Study
In one paragraph

Observational study in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Biology · 2025
    Article
  5. Divide and Conquer-Targeted Therapy for Triple-Negative Breast Cancer.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Comprehensive mapping of alternative polyadenylation site usage and its dynamics at single-cell resolution.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lei WangDepartment of Breast Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai 200032, People's Republic of China.
Guan-Tian LangDepartment of Breast Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai 200032, People's Republic of China.
Meng-Zhu XueSARI Center for Stem Cell and Nanomedicine, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, People's Republic of China.
Liu YangDepartment of Breast Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai 200032, People's Republic of China.
Li ChenDepartment of Breast Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai 200032, People's Republic of China.
Ling YaoDepartment of Breast Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai 200032, People's Republic of China.
Xiao-Guang LiDepartment of Breast Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai 200032, People's Republic of China.
Peng WangBio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, People's Republic of China.
Xin HuDepartment of Breast Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai 200032, People's Republic of China.
Zhi-Ming ShaoDepartment of Breast Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai 200032, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, NeoplasticPolyadenylation3' Untranslated RegionsApoptosisBreastCarcinogenesisCell CycleCell Line, TumorCell ProliferationCleavage And Polyadenylation Specificity FactorDisease-Free SurvivalFemaleGenetic HeterogeneityHumansMiddle AgedOligonucleotide Array Sequence Analysis3' Untranslated RegionsCleavage And Polyadenylation Specificity FactorCPSF1 protein, humanPABPN1 protein, humanPoly(A)-Binding Protein Ialternative polyadenylationCPSF1PABPN1subtypetriple-negative breast cancer

Identifiers

PMID32929364
PMCPMC7482814

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.