SynthesisEye (London, England)2021
Normative data for optical coherence tomography in children: a systematic review.
Synthesis in Eye (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Children exposed to hydroxychloroquine in utero show no signs of retinal toxicity at age 5.Lupus science & medicine · 2026Article
- Optical coherence tomography findings in Duchenne muscular dystrophy.BMC ophthalmology · 2026Article
- Comparison of Two Spectral-Domain Optical Coherence Tomographs for Macular Thickness in Romanian Children Reveals Device-Dependent Normative Data and Significant Gender Differences.Diagnostics (Basel, Switzerland) · 2026Article
- Ocular and Systemic Phenotyping of Bardet-Biedel Syndrome Type 7 (BBS7) in a Palestinian Male: Case Report and Literature Review.Case reports in ophthalmological medicine · 2026Article
- Age-Related Differences in Optical Coherence Tomography and Optical Coherence Tomography Angiography Parameters Between Healthy Children and Adults: A Comparative Analysis in a Caucasian Population.Journal of personalized medicine · 2025Article
- New Threshold for Large Optic Discs in Children Using Bruch's Membrane Opening Area.Translational vision science & technology · 2025Article
- Normative retinal thickness values in children, measured by swept-source optical coherence tomography.Medical hypothesis, discovery & innovation ophthalmology journal · 2025Article
- Article
- Normative optical coherence tomography reference ranges of the optic nerve head, nerve fiber layer, and macula in healthy Saudi children.Saudi medical journal · 2023Article
- Normative Percentiles of Retinal Nerve Fiber Layer Thickness and Glaucomatous Visual Field Loss.Translational vision science & technology · 2023Article
- Fairness and generalizability of OCT normative databases: a comparative analysis.International journal of retina and vitreous · 2023Article
- Retinal Nerve Fiber Layer Imaging with Two Different Spectral Domain Optical Coherence Tomographs: Normative Data for Romanian Children.Diagnostics (Basel, Switzerland) · 2023Article
- Infantile nystagmus without overt eye abnormality: Early features and neuro-ophthalmological diagnosis.Developmental medicine and child neurology · 2022Article
- Choroidal Thickness in a Hyperopic Pediatric Population.Diagnostics (Basel, Switzerland) · 2022Article
- Reference database of total retinal vessel surface area derived from volume-rendered optical coherence tomography angiography.Scientific reports · 2022Article
- Thicker Retinal Nerve Fiber Layer with Age among Schoolchildren: The Hong Kong Children Eye Study.Diagnostics (Basel, Switzerland) · 2022Article
- Normative Data and Determinants of Macular, Disc, and Peripapillary Vascular Density in Healthy Myopic Children Using Optical Coherence Tomography Angiography.Frontiers in medicine · 2022Article
- Posterior Pole Asymmetry Analysis in the Children with Anisometropia.Beyoglu eye journal · 2022Article
- Retinal layer segmentation in a cohort of healthy children via optical coherence tomography.PloS one · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study is to systematically review the reported data of normal optical coherence tomography (OCT) results in the paediatric population. A systematic literature search was performed using the PubMed, Embase, and Web of Science databases, using the keywords "optical coherence tomography"; "normative data" or "healthy eyes"; "children" or "paediatric population". Studies with at least 50 participants were included, irrespective of the OCT equipment employed. We excluded the OCT angiography studies or the studies investigating the choroidal thickness. Seventy-four studies were included in the final analysis and information on study design, number of participants, demographic characteristics, type of OCT equipment, OCT parameters and results was collected. Due to the high variability of OCT instruments and parameters used, a meta-analysis was not feasible. We report the normative values for the peripapillary retinal nerve fibre layer thickness and the macular retinal thickness for each ETDRS quadrant, as provided by the studies included in the present analysis. We also report the influence of ethnicity, age, gender, eye laterality, ISNT rule, spherical equivalent, and axial length on OCT results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.