ArticleNature communications2020
Chemical entrapment and killing of insects by bacteria.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Streptomyces produce a diphtheria toxin-like exotoxin that targets insects.Nature microbiology · 2026Article
- ExploringMicrobiology (Reading, England) · 2026Review
- Harnessing Microbial Volatile Organic Compounds for Crop Protection: Scientific Discovery, Bridging Ecological Function and On-Farm Application.Microbial biotechnology · 2026Review
- Streptomyces venezuelae uses secreted chitinases and a designated ABC transporter to support the competitive saprophytic catabolism of chitin.PLoS biology · 2025Article
- Agronomic Efficiency of Compost Extracts and Nitrogen-Fixing Bacteria in Soybean Crops.Microorganisms · 2025Article
- Microbial alternatives for sustainable insecticide use, a Canadian perspective.Sustainable microbiology · 2025Article
- Synthesis of Bodipy-Tagged Galactoconjugates and Evaluation of Their Antibacterial Properties.Molecules (Basel, Switzerland) · 2024Article
- Article
- Safety Assessment of the Potential Probiotic Bacterium Limosilactobacillus fermentum J23 Using the Mexican Fruit Fly (Anastrepha ludens Loew, Diptera: Tephritidae) as a Novel In Vivo Model.Probiotics and antimicrobial proteins · 2024Article
- Antibiotics from Insect-Associated Actinobacteria.Biology · 2022Review
- Analysis ofMicrobiology spectrum · 2022Article
- The secret life of insect-associated microbes and how they shape insect-plant interactions.FEMS microbiology ecology · 2022Review
- Multikingdom interactions govern the microbiome in subterranean cultural heritage sites.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Surface Design for Antibacterial Materials: From Fundamentals to Advanced Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Production of Plant-Associated Volatiles by Select Model and Industrially ImportantMicroorganisms · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Actinobacteria produce antibacterial and antifungal specialized metabolites. Many insects harbour actinobacteria on their bodies or in their nests and use these metabolites for protection. However, some actinobacteria produce metabolites that are toxic to insects and the evolutionary relevance of this toxicity is unknown. Here we explore chemical interactions between streptomycetes and the fruit fly Drosophila melanogaster. We find that many streptomycetes produce specialized metabolites that have potent larvicidal effects against the fly; larvae that ingest spores of these species die. The mechanism of toxicity is specific to the bacterium's chemical arsenal: cosmomycin D producing bacteria induce a cell death-like response in the larval digestive tract; avermectin producing bacteria induce paralysis. Furthermore, low concentrations of volatile terpenes like 2-methylisoborneol that are produced by streptomycetes attract fruit flies such that they preferentially deposit their eggs on contaminated food sources. The resulting larvae are killed during growth and development. The phenomenon of volatile-mediated attraction and specialized metabolite toxicity suggests that some streptomycetes pose an evolutionary risk to insects in nature.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.