ArticleNature communications2020
Ignoring correlated activity causes a failure of retinal population codes.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Nonuniform spike count shared variability in the mouse early visual system.Journal of neurophysiology · 2026Article
- Projection targeting with phototagging to study the structure and function of retinal ganglion cells.Cell reports methods · 2026Article
- Article
- Luminance invariant encoding in mouse primary visual cortex.Cell reports · 2025Article
- Article
- The geometry of correlated variability leads to highly suboptimal discriminative sensory coding.Journal of neurophysiology · 2025Article
- Tackling visual impairment: emerging avenues in ophthalmology.Frontiers in medicine · 2025Review
- Fixational eye movements enhance the precision of visual information transmitted by the primate retina.Nature communications · 2024Article
- Fixational Eye Movements Enhance the Precision of Visual Information Transmitted by the Primate Retina.bioRxiv : the preprint server for biology · 2024Article
- Biophysical neural adaptation mechanisms enable artificial neural networks to capture dynamic retinal computation.Nature communications · 2024Article
- Calibrating Bayesian Decoders of Neural Spiking Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Advancements in brain-machine interfaces for application in the metaverse.Frontiers in neuroscience · 2024Review
- Large-scale interrogation of retinal cell functions by 1-photon light-sheet microscopy.Cell reports methods · 2023Article
- Dynamic structure of motor cortical neuron coactivity carries behaviorally relevant information.Network neuroscience (Cambridge, Mass.) · 2023Article
- Retinal Processing: Insights from Mathematical Modelling.Journal of imaging · 2022Article
- Differences in the spatial fidelity of evoked and spontaneous signals in the degenerating retina.Frontiers in cellular neuroscience · 2022Article
- Article
- Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning.Scientific reports · 2021Article
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
From starlight to sunlight, adaptation alters retinal output, changing both the signal and noise among populations of retinal ganglion cells (RGCs). Here we determine how these light level-dependent changes impact decoding of retinal output, testing the importance of accounting for RGC noise correlations to optimally read out retinal activity. We find that at moonlight conditions, correlated noise is greater and assuming independent noise severely diminishes decoding performance. In fact, assuming independence among a local population of RGCs produces worse decoding than using a single RGC, demonstrating a failure of population codes when correlated noise is substantial and ignored. We generalize these results with a simple model to determine what conditions dictate this failure of population processing. This work elucidates the circumstances in which accounting for noise correlations is necessary to take advantage of population-level codes and shows that sensory adaptation can strongly impact decoding requirements on downstream brain areas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.