Evidence map›Paper›PMID 32928963›Full record

ArticleInfection and immunity2020

The BB0345 Hypothetical Protein of Borrelia burgdorferi Is Essential for Mammalian Infection.

Danielle E Graham, Ashley M Groshong, Clay D Jackson-Litteken, Brendan P Moore, Melissa J Caimano, Jon S Blevins

Abstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Danielle E GrahamDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Ashley M GroshongDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Clay D Jackson-LittekenDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Brendan P MooreDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Melissa J CaimanoDepartment of Medicine, University of Connecticut Health Center, Farmington, Connecticut, USA.
Jon S BlevinsDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA jsblevins@uams.edu.ORCID 0000-0001-6216-7365

Funding

Study of the Cell-specific Inflammasome Responses During Defense Against Gram-negative BacteriaP20GM103625 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI SMELTZER, MARK S · 2012 to 2021
$21.5M
RpoS Regulation of Borrelia burgdorferi Genes in vivoR01AI029735 · NIAID · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI CAIMANO, MELISSA J, RADOLF, JUSTIN D · 1990 to 2022
$10.7M
The University of Arkansas for Medical Sciences Initiative for Maximizing Student Development ProgramR25GM083247 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI MCGEHEE, ROBERT E, THOMAS, BILLY R · 2009 to 2023
$5.4M
RpoS-mediated virulence regulation in Borrelia burgdorferiR01AI087678 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI BLEVINS, JON SCOTT · 2010 to 2014
$1.8M
Essential role of Hk1/Rrp1 TCS for survival of Borrelia burgdorferi in ticksR21AI126146 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CAIMANO, MELISSA J · 2016 to 2017
$439k
Borrelia burgdorferi oligopeptide (Opp) transporter control of cellular homeostasis and growthR21AI139940 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CAIMANO, MELISSA J, RADOLF, JUSTIN D · 2018 to 2019
$439k
Rrp2-dependent gene regulation in Borrelia burgdorferiR21AI119532 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI BLEVINS, JON SCOTT · 2015 to 2016
$403k
NIAID NIH HHS R01 AI029735NIAID NIH HHS R01 AI087678NIAID NIH HHS R21 AI119532NIAID NIH HHS R21 AI126146NIGMS NIH HHS P20 GM103625NIGMS NIH HHS R25 GM083247
6 · The paper itself

Abstract

During the natural enzootic life cycle of

Indexed as

AnimalsBacterial ProteinsBorrelia burgdorferiComputational BiologyFemaleGene Expression Regulation, BacterialHost Microbial InteractionsLipoproteinsLyme DiseaseMembrane ProteinsMiceRatsRats, Sprague-DawleyRecombinant ProteinsSpirochaetalesBacterial ProteinsBB0365 protein, Borrelia burgdorferiLipoproteinsMembrane ProteinsRecombinant ProteinsBorreliaBorrelia burgdorferiBorreliellaLyme diseasemolecular geneticspathogenesisspirochetes

Identifiers

PMID32928963
PMCPMC7671889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.