Evidence map›Paper›PMID 32928887›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Activity-Dependent Global Downscaling of Evoked Neurotransmitter Release across Glutamatergic Inputs in

Shanker Karunanithi, Yong Qi Lin, G Lorenzo Odierna, Hareesh Menon, Juan Mena Gonzalez, G Gregory Neely, Peter G Noakes, Nickolas A Lavidis, Andrew J Moorhouse, Bruno van Swinderen

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Frontiers in molecular neuroscience · 2024
    Article
  2. Article
  3. Molecular Logic of Synaptic Diversity BetweenbioRxiv : the preprint server for biology · 2023
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Shanker KarunanithiQueensland Brain Institute, The University of Queensland, St. Lucia, Queensland 4072, Australia shankerkarunanithi@gmail.com.
Yong Qi LinDr. John and Anne Chong Laboratory for Functional Genomics, Charles Perkins Centre, Centenary Institute, School of Life and Environmental Sciences, The University of Sydney, NSW, 2006, Australia.
G Lorenzo OdiernaSchool of Biomedical Science, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Hareesh MenonSchool of Medical Science and Menzies Health Institute Queensland, Griffith University, Gold Coast Campus, Queensland 4222, Australia.
Juan Mena GonzalezARL Division of Neurobiology, University of Arizona, Tucson, Arizona 85721.
G Gregory NeelyDr. John and Anne Chong Laboratory for Functional Genomics, Charles Perkins Centre, Centenary Institute, School of Life and Environmental Sciences, The University of Sydney, NSW, 2006, Australia.
Peter G NoakesQueensland Brain Institute, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Nickolas A LavidisSchool of Biomedical Science, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Andrew J MoorhouseSchool of Medical Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia.
Bruno van SwinderenQueensland Brain Institute, The University of Queensland, St. Lucia, Queensland 4072, Australia.ORCID 0000-0001-6552-7418
The University of Queensland · AUThe University of Sydney · AUGriffith University · AUUniversity of Arizona · USUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Within mammalian brain circuits, activity-dependent synaptic adaptations, such as synaptic scaling, stabilize neuronal activity in the face of perturbations. Stability afforded through synaptic scaling involves uniform scaling of quantal amplitudes across all synaptic inputs formed on neurons, as well as on the postsynaptic side. It remains unclear whether activity-dependent uniform scaling also operates within peripheral circuits. We tested for such scaling in a

Indexed as

AnimalsDrosophilaEvoked PotentialsGlutamic AcidHomeostasisImmunohistochemistryLocomotionMotor NeuronsMusclesNeuromuscular JunctionNeurotransmitter AgentsPatch-Clamp TechniquesSynapsesSynaptic PotentialsVesicular Glutamate Transport ProteinsGlutamic AcidNeurotransmitter AgentsVesicular Glutamate Transport ProteinsDrosophila neuromuscular junctionfiring rateshomeostatic plasticitymotor patternsquantal contentsynaptic scaling

Identifiers

PMID32928887
PMCPMC7574657
OpenAlexW3085452116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.