Evidence map›Paper›PMID 32928340›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2020

Injection-site Reactions to Sustained-release Meloxicam in Sprague-Dawley Rats.

Leslie A Stewart, Denise M Imai, Laurel Beckett, Yueju Li, K C Lloyd, Kristin N Grimsrud

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Pharmacokinetics and Analgesic Efficacy of a Novel Extended-Release Buprenorphine Formulation in Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A Review of Long-acting Parenteral Analgesics for Mice and Rats.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Review
  8. Extended-release Buprenorphine, an FDAindexed Analgesic, Attenuates Mechanical Hypersensitivity in Rats (Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Leslie A StewartMouse Biology Program, School of Medicine, University of California-Davis, Davis, California.
Denise M ImaiComparative Pathology Laboratory, School of Medicine, University of California-Davis, Davis, California; School of Veterinary Medicine, School of Medicine, University of California-Davis, Davis, California.
Laurel BeckettDivision of Biostatistics, Department of Public Health Sciences, School of Medicine, University of California-Davis, Davis, California.
Yueju LiDivision of Biostatistics, Department of Public Health Sciences, School of Medicine, University of California-Davis, Davis, California.
K C LloydMouse Biology Program, School of Medicine, University of California-Davis, Davis, California; Department of Surgery, School of Medicine, University of California-Davis, Davis, California.
Kristin N GrimsrudMouse Biology Program, School of Medicine, University of California-Davis, Davis, California; Department of Pathology and Laboratory Medicine, School of Medicine, University of California-Davis, Davis, California;, Email: kngrimsrud@ucdavis.edu.
University of California, Davis · US

Funding

Characterizing the Impact of Genetic Polymorphism on Fentanyl Efficacy and Tolerance in PediatricsK01OD026608 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GRIMSRUD, KRISTIN NICOLE · 2019 to 2023
$731k
NIH HHS K01 OD026608
6 · The paper itself

Abstract

An extended-release formulation of the NSAID meloxicam (MSR) is used to provide 72 h of continuous analgesia in many species, including rodents. Although standard formulations of meloxicam are frequently used in rats with no observable injection-site reactions, the potential adverse effects from MSR have not been characterized sufficiently nor has a prospective study of these effects been performed in rats. To address this deficiency, we evaluated injection-site reactions after a single subcutaneous administration of MSR (

Indexed as

Rats, Sprague-DawleyAnalgesiaAnimalsAnti-Inflammatory Agents, Non-SteroidalDelayed-Action PreparationsFemaleMaleMeloxicamPainProspective StudiesRatsAnti-Inflammatory Agents, Non-SteroidalDelayed-Action PreparationsMeloxicam

Identifiers

PMID32928340
PMCPMC7604686
OpenAlexW3087616215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.