Evidence map›Paper›PMID 32928037›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2021

Airborne Aerosolized Mouse Cytomegalovirus From Common Otolaryngology Procedures: Implications for COVID-19 Infection.

Tofigh Sayahi, Christopher Nielson, Yuan Yu, Kaden Neuberger, Michael Seipp, Matthew A Firpo, Kerry Kelly, Albert H Park

Erratum issuedAbstract read
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Tofigh SayahiDepartment of Chemical Engineering, University of Utah, Salt Lake City, Utah, USA.
Christopher NielsonDivision of Otolaryngology-Head and Neck Surgery, University of Utah, Salt Lake City, Utah, USA.
Yuan YuDivision of Otolaryngology-Head and Neck Surgery, University of Utah, Salt Lake City, Utah, USA.
Kaden NeubergerDivision of Otolaryngology-Head and Neck Surgery, University of Utah, Salt Lake City, Utah, USA.
Michael SeippDepartment of Surgery, University of Utah, Salt Lake City, Utah, USA.
Matthew A FirpoDepartment of Surgery, University of Utah, Salt Lake City, Utah, USA.
Kerry KellyDepartment of Chemical Engineering, University of Utah, Salt Lake City, Utah, USA.
Albert H ParkDivision of Otolaryngology-Head and Neck Surgery, University of Utah, Salt Lake City, Utah, USA.

Funding

Linking Combustion-Derived Particle Physicochemical Properties to Pathologically Important Responses in Lung CellsK25ES027504 · NIEHS · UNIVERSITY OF UTAH · PI KELLY, KERRY · 2017 to 2021
$771k
MSRP in Metabolism, Diabetes, Digestive and Kidney DiseasesT35DK103596 · NIDDK · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI BEDDHU, SRINIVASAN, ROUND, JUNE LOUISE · 2015 to 2025
$758k
NIEHS NIH HHS K25 ES027504
6 · The paper itself

Abstract

objectivesTo determine whether common otolaryngology procedures generate viable aerosolized virus through a murine cytomegalovirus (mCMV) model for infection. STUDY

designmCMV model of infection.

settingUniversity of Utah laboratory.

methodsThree-day-old BALB/c mice were inoculated with mCMV or saline. Five days later, each mouse underwent drilling, microdebrider, coblation, and electrocautery procedures. Particle size distribution and PM

resultsAs compared with the background aerosol concentrations, coblation and electrocautery showed statistically significant increases in airborne aerosols (Tukey-adjusted

conclusionCoblation and electrocautery procedures generate >100-fold increases in aerosol concentrations over background; only coblation and drilling produce aerosolized viral DNA. The high concentration of aerosols from coblation and electrocautery suggests the need for appropriate safeguards against particle exposure to health care workers. The presence of viral DNA from drilling and coblation procedures warrants the need for appropriate protection against droplet and aerosol exposure.

Indexed as

Air MicrobiologyCOVID-19Otorhinolaryngologic Surgical ProceduresAerosolsAnimalsMiceMice, Inbred BALB CMuromegalovirusAerosolsaerosol-generating procedureaerosolizationairborneCOVID-19cytomegalovirusotolaryngology surgical procedures

Identifiers

PMID32928037
PMCPMC7492827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.