Evidence map›Paper›PMID 32927913›Full record

ReviewToxins2020

Staphylococcal Enterotoxin C-An Update on SEC Variants, Their Structure and Properties, and Their Role in Foodborne Intoxications.

Danai Etter, Jenny Schelin, Markus Schuppler, Sophia Johler

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
0.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 51 citations in OpenAlex.

  1. Qualitative assessment of virulence and resistance gene transcripts in Staphylococcus aureus isolated from buffalo milk and dairy products.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Increased occurrence ofOne health (Amsterdam, Netherlands) · 2025
    Article
  7. Clarifying the Dual Role ofFoods (Basel, Switzerland) · 2025
    Review
  8. Raw Sheep Milk as a Reservoir of Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. CanineMicrobiology spectrum · 2024
    Article
  17. Article
  18. [Screening of pathogenic molecular markers ofZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Danai EtterInstitute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zürich, 8057 Zürich, Switzerland.ORCID 0000-0002-6623-4091
Jenny SchelinDivision of Applied Microbiology, Department of Chemistry, Lund University, 22100 Lund, Sweden.ORCID 0000-0001-5564-6309
Markus SchupplerLaboratory of Food Microbiology, Institute of Food, Nutrition and Health, ETH Zürich, 8092 Zürich, Switzerland.
Sophia JohlerInstitute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zürich, 8057 Zürich, Switzerland.ORCID 0000-0003-4299-5651
University of Zurich · CHETH Zurich · CHLund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Staphylococcal enterotoxins are the most common cause of foodborne intoxications (staphylococcal food poisoning) and cause a wide range of diseases. With at least six variants staphylococcal enterotoxin C (SEC) stands out as particularly diverse amongst the 25 known staphylococcal enterotoxins. Some variants present unique and even host-specific features. Here, we review the role of SEC in human and animal health with a particular focus on its role as a causative agent for foodborne intoxications. We highlight structural features unique to SEC and its variants, particularly, the emetic and superantigen activity, as well as the roles of SEC in mastitis and in dairy products. Information about the genetic organization as well as regulatory mechanisms including the accessory gene regulator and food-related stressors are provided.

Indexed as

Food MicrobiologyAnimal FeedAnimalsAntigens, BacterialEnterotoxinsGenetic VariationHost SpecificityHumansProtein ConformationStaphylococcal Food PoisoningStaphylococcusStructure-Activity RelationshipSuperantigensVirulenceAntigens, Bacterialenterotoxin C, staphylococcalEnterotoxinsSuperantigensemesishost specificitySECstaphylococcal food poisoningsuperantigen

Identifiers

PMID32927913
PMCPMC7551944
OpenAlexW3084670731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.