Evidence map›Paper›PMID 32927716›Full record

SynthesisMolecules (Basel, Switzerland)2020

Vibrational Spectroscopy Saliva Profiling as Biometric Tool for Disease Diagnostics: A Systematic Literature.

Stéphane Derruau, Julien Robinet, Valérie Untereiner, Olivier Piot, Ganesh D Sockalingum, Sandrine Lorimier

Abstract readSystematic Review
In one paragraph

Synthesis in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stéphane DerruauDépartement de Biologie Orale, UFR Odontologie, Université de Reims Champagne-Ardenne, 2 rue du Général Koenig, 51100 Reims, France.
Julien RobinetDépartement de Biologie Orale, UFR Odontologie, Université de Reims Champagne-Ardenne, 2 rue du Général Koenig, 51100 Reims, France.
Valérie UntereinerPICT, Université de Reims Champagne-Ardenne, 51 rue Cognacq-Jay, 51097 Reims, France.
Olivier PiotBioSpecT-EA7506, UFR de Pharmacie, Université de Reims Champagne-Ardenne, 51 rue Cognacq-Jay, 51097 Reims, France.
Ganesh D SockalingumBioSpecT-EA7506, UFR de Pharmacie, Université de Reims Champagne-Ardenne, 51 rue Cognacq-Jay, 51097 Reims, France.ORCID 0000-0003-3160-4678
Sandrine LorimierDépartement de Biologie Orale, UFR Odontologie, Université de Reims Champagne-Ardenne, 2 rue du Général Koenig, 51100 Reims, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saliva is a biofluid that can be considered as a "mirror" reflecting our body's health status. Vibrational spectroscopy, Raman and infrared, can provide a detailed salivary fingerprint that can be used for disease biomarker discovery. We propose a systematic literature review based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines to evaluate the potential of vibrational spectroscopy to diagnose oral and general diseases using saliva as a biological specimen. Literature searches were recently conducted in May 2020 through MEDLINE-PubMed and Scopus databases, without date limitation. Finally, over a period of 10 years, 18 publications were included reporting on 10 diseases (three oral and seven general diseases), with very high diagnostic performance rates in terms of sensitivity, specificity, and accuracy. Thirteen articles were related to six different cancers of the following anatomical sites: mouth, nasopharynx, lung, esophagus, stomach, and breast. The other diseases investigated and included in this review were periodontitis, Sjögren's syndrome, diabetes, and myocardial infarction. Moreover, most articles focused on Raman spectroscopy (

Indexed as

BiomarkersBiometryMolecular Diagnostic TechniquesSpectrum Analysis, RamanAnimalsHumansMetabolomicsSalivaSensitivity and SpecificitySpectroscopy, Fourier Transform InfraredBiomarkersdiagnosisinfraredRamansalivasystematic reviewvibrational spectroscopy

Identifiers

PMID32927716
PMCPMC7570680

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.