Evidence map›Paper›PMID 32927694›Full record

ArticleLife (Basel, Switzerland)2020

The Molecular Effects of a High Fat Diet on Endometrial Tumour Biology.

Michael Wilkinson, Piriyah Sinclair, Ludmilla Dellatorre-Teixeira, Patrick Swan, Eoin Brennan, Bruce Moran, Dirk Wedekind, Paul Downey, Kieran Sheahan, Emer Conroy and 4 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Michael WilkinsonDepartment of Gynaecological Oncology, UCD School of Medicine, Mater Misericordiae Universtity Hospital, Eccles Street, Dublin 7, D07 AX57 Dublin, Ireland.
Piriyah SinclairUCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.
Ludmilla Dellatorre-TeixeiraUCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.
Patrick SwanUCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.
Eoin BrennanUCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.
Bruce MoranDepartment of Pathology, St Vincent's University Hospital, Elm Park, Dublin 4, D04 YN63 Dublin, Ireland.ORCID 0000-0002-7266-0265
Dirk WedekindBiomedical Facility, Hanover Medical School, 30625 Hanover, Germany.ORCID 0000-0002-4027-9662
Paul DowneyDepartment of Pathology, National Maternity Hospital, Holles Street, Dublin 2, D02 YH21 Dublin, Ireland.
Kieran SheahanDepartment of Pathology, St Vincent's University Hospital, Elm Park, Dublin 4, D04 YN63 Dublin, Ireland.
Emer ConroyCancer Biology and Therapeutic Laboratory, UCD School of Biomolecular and Biomedical Science Ireland, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.
William M GallagherCancer Biology and Therapeutic Laboratory, UCD School of Biomolecular and Biomedical Science Ireland, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.ORCID 0000-0002-4307-5999
Neil DochertyUCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.
Carel le RouxUCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.
Donal J BrennanDepartment of Gynaecological Oncology, UCD School of Medicine, Mater Misericordiae Universtity Hospital, Eccles Street, Dublin 7, D07 AX57 Dublin, Ireland.ORCID 0000-0002-6747-3342
University College Dublin · IESt. Vincent's University Hospital · IEMedizinische Hochschule Hannover · DENational Maternity Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We sought to validate the BDII/Han rat model as a model for diet-induced obesity in endometrial cancer (EC) and determine if transcriptomic changes induced by a high fat diet (HFD) in an EC rat model can be used to identify novel biomarkers in human EC. Nineteen BDII/Han rats were included. Group A (

Indexed as

endometrial cancerobesitytranscriptomics

Identifiers

PMID32927694
PMCPMC7554710
OpenAlexW3086746951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.