Evidence map›Paper›PMID 32927677›Full record

Trial reportNutrients2020

Black Soybean Improves Vascular Function and Blood Pressure: A Randomized, Placebo Controlled, Crossover Trial in Humans.

Yoko Yamashita, Asuka Nakamura, Fumio Nanba, Shizuka Saito, Toshiya Toda, Junichi Nakagawa, Hitoshi Ashida

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yoko YamashitaDepartment of Agrobioscience, Graduate School of Agricultural Science, Kobe University, 1-1, Rokkodai-cho, Nada-ku, Kobe 657-8501, Japan.
Asuka NakamuraDepartment of Agrobioscience, Graduate School of Agricultural Science, Kobe University, 1-1, Rokkodai-cho, Nada-ku, Kobe 657-8501, Japan.
Fumio NanbaFujicco Co. Ltd., Research Development, 6-13-4, Minatojima-Nakamachi, Chuo-Ku, Kobe 650-8558, Japan.
Shizuka SaitoFujicco Co. Ltd., Research Development, 6-13-4, Minatojima-Nakamachi, Chuo-Ku, Kobe 650-8558, Japan.
Toshiya TodaFujicco Co. Ltd., Research Development, 6-13-4, Minatojima-Nakamachi, Chuo-Ku, Kobe 650-8558, Japan.ORCID 0000-0002-7559-7302
Junichi NakagawaNakagawa Clinic, 3-15-4, Higashisonoda-cho, Amagasaki 661-0953, Japan.
Hitoshi AshidaDepartment of Agrobioscience, Graduate School of Agricultural Science, Kobe University, 1-1, Rokkodai-cho, Nada-ku, Kobe 657-8501, Japan.
Kobe University · JP

Funding

Cabinet Office, Government of Japan, and Japan Society 17H00818
6 · The paper itself

Abstract

Vascular dysfunction and injurious stimuli such as oxidative stress are closely related to the risk of cardiovascular diseases (CVD). Dietary polyphenols are reported to exert beneficial effects in reducing the risk of CVD. Black soybean has been used as a nutritionally rich food and contains abundant polyphenols in its seed coat and grain. Black soybean has many beneficial physiological activities, and its prevention effects on CVD risk were reported mainly in animal experiments. In this study, we performed a randomized, single blind, placebo controlled, crossover trial to investigate the effect of black soybean consumption on the vascular function in healthy humans. Twenty-two healthy adults aged from 30 to 60 completed the four week trial with daily consumption of about a 40 g test material cookie containing 20 g roasted black soybean powder. Body composition, vascular function, biomarkers for oxidative stress, and polyphenol contents in the urine and the plasma were measured. After ingestion of the black soybean cookie, vascular function, which was evaluated by plethysmogram using a Pulse Analyzer

Indexed as

Glycine maxAdultBiomarkersBlood PressureCardiovascular DiseasesCardiovascular Physiological PhenomenaCross-Over StudiesFemaleHealthy VolunteersHumansMaleMiddle AgedNitric OxideOxidative StressPlethysmographyPolyphenolsBiomarkersNitric OxidePolyphenolsblack soybeanblood pressureoxidative stresspolyphenolvascular function

Identifiers

PMID32927677
PMCPMC7551904
OpenAlexW3083973952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.