Evidence map›Paper›PMID 32927623›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Adsorption of Cellulase on Wrinkled Silica Nanoparticles with Enhanced Inter-Wrinkle Distance.

Aniello Costantini, Virginia Venezia, Giulio Pota, Aurelio Bifulco, Valeria Califano, Filomena Sannino

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Enzymes for Biomass Pretreatment: A Comprehensive Review.Advances in biochemical engineering/biotechnology · 2025
    Review
  2. Review
  3. Controlling the Adsorption of β-Glucosidase onto Wrinkled SiOLangmuir : the ACS journal of surfaces and colloids · 2023
    Article
  4. Review
  5. Article
  6. Article
  7. Solvent-Free One-Pot Synthesis of Epoxy Nanocomposites Containing Mg(OH)Langmuir : the ACS journal of surfaces and colloids · 2022
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aniello CostantiniDepartment of Chemical Engineering, Materials and Industrial Production, Università degli Studi di Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy.
Virginia VeneziaDepartment of Chemical Engineering, Materials and Industrial Production, Università degli Studi di Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy.ORCID 0000-0002-6368-2681
Giulio PotaDepartment of Chemical Engineering, Materials and Industrial Production, Università degli Studi di Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy.
Aurelio BifulcoDepartment of Chemical Engineering, Materials and Industrial Production, Università degli Studi di Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy.ORCID 0000-0002-4214-5385
Valeria CalifanoIstituto Motori, Italian National Research Council, via G. Marconi 4, 80125 Napoli, Italy.
Filomena SanninoDepartment of Agricultural Sciences, Università degli Studi di Napoli Federico II, Via Università 100, 80055 Portici, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesoporous silica materials offer a unique opportunity for enzyme immobilization thanks to their properties, such as tuneable pore size, large surface area and easy functionalization. However, a significant enhancement of cellulase enzyme activity entrapped inside the silica pores still represents a challenge. In this work, we immobilized cellulase by adsorption on wrinkled silica nanoparticles (WSNs), obtaining an active and stable biocatalyst. We used pentanol as co-solvent to synthesize WSNs with enhanced inter-wrinkle distance in order to improve cellulase hosting. The physical-chemical and morphological characterization of WSNs and cellulase/WSNs was performed by thermogravimetric (TG), Fourier transform infrared (FT-IR), and transmission electron microscopy (TEM) analyses. The obtained results showed that this matrix generates a favourable microenvironment for hosting cellulase. The results of the catalytic assays and operational stability confirmed the key role of size, morphology and distribution of the pores in the successful outcome of the cellulase immobilization process. The immobilization procedure used allowed preserving most of the secondary structure of the enzyme and, consequently, its catalytic activity. Moreover, the same value of glucose yield was observed for five consecutive runs, showing a high operational stability of the biocatalyst.

Indexed as

cellulaseenzyme immobilizationmesoporous nanoparticleswrinkled silica

Identifiers

PMID32927623
PMCPMC7560002

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.