Evidence map›Paper›PMID 32927501›Full record

ArticleThe international journal of medical robotics + computer assisted surgery : MRCAS2020

Focused ultrasound robotic system for very small bore magnetic resonance imaging.

Christakis Damianou, Marinos Giannakou, Nikolas Evripidou, Stefan Kegel, Peter Huber, Juergen Jenne

Abstract read
In one paragraph

Article in The international journal of medical robotics + computer assisted surgery : MRCAS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Robotic device for transcranial focussed ultrasound applications in small animal models.The international journal of medical robotics + computer assisted surgery : MRCAS · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christakis DamianouElectrical Engineering and Computer Engineering and Informatics Department, Cyprus University of Technology, Limassol, Cyprus.ORCID https://orcid.org/0000-0003-0424-2851
Marinos GiannakouElectrical Engineering and Computer Engineering and Informatics Department, Cyprus University of Technology, Limassol, Cyprus.ORCID https://orcid.org/0000-0002-6777-0515
Nikolas EvripidouElectrical Engineering and Computer Engineering and Informatics Department, Cyprus University of Technology, Limassol, Cyprus.
Stefan KegelGerman Cancer Research Center (DKFZ), Heidelberg, Germany.
Peter HuberGerman Cancer Research Center (DKFZ), Heidelberg, Germany.
Juergen JenneMEDIRI GmbH, Heidelberg, Germany.

Funding

Research Promotion foundation of Cyprus ENTERPRISES/0618/0016Research Promotion Foundation of Cyprus ENTERPRISES/0618/0016
6 · The paper itself

Abstract

backgroundA magnetic resonance imaging (MRI) compatible robotic system for focused ultrasound was developed for small animal like mice or rats that fits into a 9.4 T MRI scanner (Bruker Biospec 9420, Bruker Biospin, Ettlingen, Germany). The robotic system includes two computer-controlled linear stages. MATERIALS AND

methodsThe robotic system was evaluated in a mouse-shaped, real-size agar-based mimicking material, which has similar acoustical properties as soft tissues. The agar content was 6% weight per volume (w/v), 4% w/v silica while the rest was degassed water. The transducer used has a diameter of 4 cm, operates with 2.6 MHz and focuses energy at 5 cm.

resultsThe MRI compatibility of the robotic system was evaluated in a 9.4 T small animal scanner. The efficacy of the ultrasonic transducer was evaluated in the mimicking material using temperature measurements.

conclusionsThe proposed robotic system can be utilized in a 9.4 T small animal MRI scanner. The proposed system is functional, compact and simple thus providing a useful tool for preclinical research in mice and rats.

Indexed as

Robotic Surgical ProceduresAnimalsMagnetic Resonance ImagingMicePhantoms, ImagingRatsTransducersUltrasonicsHIFUMRgFUSMRIpositioningrobotic system

Identifiers

PMID32927501
PMCPMC7816236

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.