Evidence map›Paper›PMID 32926627›Full record

ArticleMolecular pharmaceutics2020

Hypoxia-Responsive, Polymeric Nanocarriers for Targeted Drug Delivery to Estrogen Receptor-Positive Breast Cancer Cell Spheroids.

Babak Mamnoon, Li Feng, Jamie Froberg, Yongki Choi, Venkatachalem Sathish, Sanku Mallik

Open access · greenAbstract read
In one paragraph

Article in Molecular pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Stimuli-responsive bioengineered platforms for precision cancer therapy.Frontiers in bioengineering and biotechnology · 2026
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  11. A review on lipid and polymeric nano-based 17-β-estradiol delivery systems: advances and challenges.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Babak MamnoonDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58102, United States.
Li FengDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58102, United States.
Jamie FrobergDepartment of Physics, North Dakota State University, Fargo, North Dakota 58102, United States.
Yongki ChoiDepartment of Physics, North Dakota State University, Fargo, North Dakota 58102, United States.ORCID 0000-0001-8890-8344
Venkatachalem SathishDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58102, United States.
Sanku MallikDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58102, United States.ORCID 0000-0003-4236-2512
North Dakota State University · US

Funding

Targeting CLEC-2/podoplanin as a therapeutic strategy for pancreatic cancerP20GM109024 · NIGMS · NORTH DAKOTA STATE UNIVERSITY · PI Megan Orr · 2016 to 2026
$20.5M
Tracking and Evaluation CoreU54GM128729 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI BASSON, MARC D. · 2018 to 2022
$20.3M
Echogenic Polymersomes for Triggered Contents ReleaseR01GM114080 · NIGMS · NORTH DAKOTA STATE UNIVERSITY · PI MALLIK, SANKU, SARKAR, KAUSIK · 2015 to 2023
$2.6M
NIGMS NIH HHS P20 GM109024NIGMS NIH HHS R01 GM114080NIGMS NIH HHS U54 GM128729
6 · The paper itself

Abstract

Uncontrolled cell growth, division, and lack of enough blood supply causes low oxygen content or hypoxia in cancerous tumor microenvironments. 17β-Estradiol (E

Indexed as

Antineoplastic AgentsBreast NeoplasmsCell HypoxiaCell SurvivalDoxorubicinDrug CarriersEstradiolFemaleHumansLigandsMCF-7 CellsNanoparticlesPolymersReceptors, EstrogenSpheroids, CellularTumor MicroenvironmentAntineoplastic AgentsDoxorubicinDrug CarriersEstradiolLigandsPolymersReceptors, Estrogenbreast cancerestrogen receptorhypoxiapolymersomestargeted drug delivery

Identifiers

PMID32926627
PMCPMC8095663
OpenAlexW3085977930

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.