ReviewCurrent hypertension reports2020
Preeclampsia and Kidney Disease: Deciphering Cause and Effect.
Review in Current hypertension reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 70 citations in OpenAlex.
- The pathophysiology of pre-eclampsia.Nature reviews. Nephrology · 2026Review
- Impact of Preeclampsia on Long-Term Kidney Function in a Low-Resourced Setting.Kidney international reports · 2026Article
- Blood Pressure, Urinalysis, and Edema Assessment in Perinatal Care: From Historical Foundations to Evidence-Based Practice.JMA journal · 2026Review
- Article
- Short-term preeclampsia prediction: cutoff variations for sFlt-1/PlGF in U.S. Patients with or without hypertensive disorders.Annals of medicine · 2025Article
- Long-Term Biochemical and Cardiovascular Profiles 3-6 Years After Preeclampsia: Impact of Angiogenic Imbalance During Pregnancy.Journal of clinical medicine · 2025Article
- Subclinical Postpartum Renal Structure After Hypertensive Pregnancy Disorders.Hypertension (Dallas, Tex. : 1979) · 2025Article
- Potential Molecular Biomarkers of Preeclampsia-A Pilot Study.International journal of molecular sciences · 2025Article
- Pregnancy in Women Receiving Maintenance Dialysis.Kidney medicine · 2025Review
- A Review of Dietary and Lifestyle Management of Pre-Eclampsia and Postpartum Eclampsia.Preventive nutrition and food science · 2025Review
- Metabolic profiles of meconium in preeclamptic and normotensive pregnancies.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Steroid Profiles and Precursor-to-Product Ratios Are Altered in Pregnant Women with Preeclampsia.International journal of molecular sciences · 2024Article
- Multi-Omics Integration in Nephrology: Advances, Challenges, and Future Directions.Seminars in nephrology · 2024Review
- Metabolic theory of preeclampsia: implications for maternal cardiovascular health.American journal of physiology. Heart and circulatory physiology · 2024Review
- The interval between the onset of increased blood pressure and proteinuria in preeclampsia and the contributing factors.Archives of gynecology and obstetrics · 2024Article
- Risk factors for preeclampsia in patients with chronic kidney disease primarily focused on stage 1 CKD. Are referred and registered patients alike?Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Impact of Pregnancy on the Pharmacokinetics and Metabolism of Nicotinamide in Humans.Clinical pharmacology and therapeutics · 2024Article
- Review
- Protein Misfolding in Pregnancy: Current Insights, Potential Mechanisms, and Implications for the Pathogenesis of Preeclampsia.Molecules (Basel, Switzerland) · 2024Review
- A Prediction Model of Preeclampsia in Hyperglycemia Pregnancy.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewPreeclampsia and chronic kidney disease have a complex, bidirectional relationship. Women with kidney disease, with even mild reductions in glomerular filtrate rate, have an increased risk of developing preeclampsia. Preeclampsia, in turn, has been implicated in the subsequent development of albuminuria, chronic kidney disease, and end-stage kidney disease. We will discuss observational evidence and mechanisms linking the two disease processes. RECENT
findingsPreeclampsia is characterized by an imbalance in angiogenic factors that causes systemic endothelial dysfunction. Chronic kidney disease may predispose to the development of preeclampsia due to comorbid conditions, such as hypertension, but is also associated with impaired glycocalyx integrity and alterations in the complement and renin-angiotensin-aldosterone systems. Preeclampsia may lead to kidney disease by causing acute kidney injury, endothelial damage, and podocyte loss. Preeclampsia may be an important sex-specific risk factor for chronic kidney disease. Understanding how chronic kidney disease increases the risk of preeclampsia from a mechanistic standpoint may open the door to future biomarkers and therapeutics for all women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.