Evidence map›Paper›PMID 32926254›Full record

ArticleMolecular diversity2021

Synthesis of 3,3'-methylenebis(4-hydroxyquinolin-2(1H)-ones) of prospective anti-COVID-19 drugs.

Ashraf A Aly, Alaa A Hassan, Asmaa H Mohamed, Esraa M Osman, Stefan Bräse, Martin Nieger, Mahmoud A A Ibrahim, Sara M Mostafa

Abstract read
In one paragraph

Article in Molecular diversity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Autoxidation of 4-Hydrazinylquinolin-2(1Molecules (Basel, Switzerland) · 2022
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashraf A AlyDepartment of Chemistry, Faculty of Science, Minia University, Minia, 61519, Egypt. ashrafaly63@yahoo.com.ORCID http://orcid.org/0000-0002-0314-3408
Alaa A HassanDepartment of Chemistry, Faculty of Science, Minia University, Minia, 61519, Egypt.
Asmaa H MohamedDepartment of Chemistry, Faculty of Science, Minia University, Minia, 61519, Egypt.
Esraa M OsmanDepartment of Chemistry, Faculty of Science, Minia University, Minia, 61519, Egypt.
Stefan BräseInstitute of Organic Chemistry, Karlsruhe Institute of Technology, 76131, Karlsruhe, Germany.
Martin NiegerDepartment of Chemistry, University of Helsinki, A. I. Virtasenaukio I, P.O. Box 55, 00014, Helsinki, Finland.
Mahmoud A A IbrahimDepartment of Chemistry, Faculty of Science, Minia University, Minia, 61519, Egypt.
Sara M MostafaDepartment of Chemistry, Faculty of Science, Minia University, Minia, 61519, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During formylation of 2-quinolones by DMF/Et

Indexed as

COVID-19 Drug TreatmentAntiviral AgentsCoronavirus 3C ProteasesDarunavirHumansHydrogen BondingMolecular Docking SimulationMolecular Dynamics SimulationProtease InhibitorsQuinolonesSARS-CoV-2Antiviral AgentsCoronavirus 3C ProteasesDarunavirProtease InhibitorsQuinolones3,3′-methylenebis(4-hydroxyquinolin-2(1H)-ones)Anti-formCOVID-19FormylationMolecular dockingX-ray

Identifiers

PMID32926254
PMCPMC7487287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.