ArticleThe Journal of cell biology1988
Yeast vacuoles fragment when microtubules are disrupted.
Article in The Journal of cell biology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 47 citations in OpenAlex.
- Lipid droplet autophagy in the yeast Saccharomyces cerevisiae.Molecular biology of the cell · 2014Article
- A screening assay based on host-pathogen interaction models identifies a set of novel antifungal benzimidazole derivatives.Antimicrobial agents and chemotherapy · 2011Article
- Prion formation and polyglutamine aggregation are controlled by two classes of genes.PLoS genetics · 2011Article
- Furfural induces reactive oxygen species accumulation and cellular damage in Saccharomyces cerevisiae.Biotechnology for biofuels · 2010Article
- PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans.The Journal of clinical investigation · 2008Article
- Genomic analysis of homotypic vacuole fusion.Molecular biology of the cell · 2002Article
- Article
- Actin and myosin function in directed vacuole movement during cell division in Saccharomyces cerevisiae.The Journal of cell biology · 1996Article
- Organelle-cytoskeletal interactions: actin mutations inhibit meiosis-dependent mitochondrial rearrangement in the budding yeast Saccharomyces cerevisiae.Molecular biology of the cell · 1995Article
- ACT3: a putative centractin homologue in S. cerevisiae is required for proper orientation of the mitotic spindle.The Journal of cell biology · 1994Article
- Dynamin: motor protein or regulatory GTPase.Journal of muscle research and cell motility · 1992Review
- vac2: a yeast mutant which distinguishes vacuole segregation from Golgi-to-vacuole protein targeting.The EMBO journal · 1991Article
- Trigger factor depletion or overproduction causes defective cell division but does not block protein export.Journal of bacteriology · 1990Article
- The fungal vacuole: composition, function, and biogenesis.Microbiological reviews · 1990Review
- Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting.The Journal of cell biology · 1988Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
To identify whether microtubules are involved in the maintenance of vacuolar morphology, we treated Saccharomyces cerevisiae with nocodazole and methyl benzimidazole-2-yl-carbamate, drugs which inhibit the polymerization of microtubules. Treated cells arrest with a single large bud in the G2/prophase portion of the cell cycle. Labeling the vacuole with either quinacrine or FITC-dextran revealed vacuole fragmentation that was not found in untreated cells or in cells arrested in G2 by unrelated means. A drug-resistant mutant in beta tubulin does not show vacuolar fragmentation when treated with drug. We propose that microtubules are involved in the regulation of vacuole morphology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.