Evidence map›Paper›PMID 32925078›Full record

ReviewJournal of Alzheimer's disease : JAD2020

COVID-19: Review of a 21st Century Pandemic from Etiology to Neuro-psychiatric Implications.

Vicky Yamamoto, Joe F Bolanos, John Fiallos, Susanne E Strand, Kevin Morris, Sanam Shahrokhinia, Tim R Cushing, Lawrence Hopp, Ambooj Tiwari, Robert Hariri and 26 more

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of Alzheimer's disease : JAD, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Exploring the Potential Medicinal Benefits ofFoods (Basel, Switzerland) · 2023
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 11 institutions in 2 countries.

Vicky YamamotoSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Joe F BolanosSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
John FiallosSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Susanne E StrandSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Kevin MorrisSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Sanam ShahrokhiniaCedars-Sinai Medical Center, Department of Nutrition, Los Angeles, CA, USA.
Tim R CushingUCLA-Cedar-Sinai California Rehabilitation Institute, Los Angeles, CA, USA.
Lawrence HoppCedars Sinai Medical Center Department of Ophthalmology and UCLA Jules Stein Eye Institute, Los Angeles, CA, USA.
Ambooj TiwariSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Robert HaririSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Rick SokolovCedars-Sinai Medical Center, Department of Infectious Disease Los Angeles, CA, USA.
Christopher WheelerSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Ajeet KaushikNanoBioTech Laboratory, Department of Natural Sciences, Division of Sciences, Arts, and Mathematics, Florida Polytechnic University, Lakeland, FL, USA.
Ashraf ElsayeghCedars Sinai Medical Center, Department of Pulmonology, Los Angeles, CA, USA.
Dawn EliashivSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Rebecca HedrickCedars Sinai Medical Center, Department of Psychiatry, Los Angeles, CA, USA.
Behrouz JafariUniversity of California, Irvine, School of Medicine, Department of Medicine, Irvine, CA, USA.
J Patrick JohnsonCedars Sinai Medical Center, Spine Institute, Los Angeles, CA, USA.
Mehran KhorsandiCedars-Sinai Medical Center, Department of Cardiology, Los Angeles, CA, USA.
Nestor GonzalezCedars-Sinai Medical Center, Department of Neurosurgery, Los Angeles, CA, USA.
Guita BalakhaniCedars-Sinai Medical Center, Department of Nephrology, Los Angeles, CA, USA.
Shouri LahiriCedars-Sinai Medical Center, Department of Neurology, Los Angeles, CA, USA.
Kazem GhavidelUniversity of Tehran School of Medicine, Department of Cardiology, Tehran, Iran.
Marco AmayaSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Harry KloorSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Namath HussainSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Edmund HuangCedars-Sinai Medical Center, Department of Nephrology, Los Angeles, CA, USA.
Jason CormierSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
J Wesson AshfordSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Jeffrey C WangSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Shadi YaghobianCedars-Sinai Medical Center, Department of Internal Medicine, Los Angeles, CA, USA.
Payman KhorramiCedars Sinai Medical Center, Department of Gastroenterology, Los Angeles, CA, USA.
Bahman ShamlooCedars Sinai Medical Center, Pain Management, Los Angeles, CA, USA.
Charles MoonCedars Sinai Orthopaedic Center, Department of Orthopedics, Los Angeles, CA, USA.
Payam ShadiCedars-Sinai Medical Center, Department of Internal Medicine, Los Angeles, CA, USA.
Babak KatebSociety for Brain Mapping and Therapeutics (SBMT), Los Angeles, CA, USA.
Cedars-Sinai Medical Center · USBrain Mapping Foundation · USCornell University · USFlorida Polytechnic University · USKeck Hospital of USC · USLoma Linda University · USNew York University · USOrthopaedic Center · USUniversity of California, Irvine · USUniversity of California, Los Angeles · USUniversity of Tehran · IR

Funding

Neuropathology of Cognitive Impairment in Critical IllnessR03AG064106 · NIA · CEDARS-SINAI MEDICAL CENTER · PI LAHIRI, SHOURI · 2019 to 2020
$255k
NIA NIH HHS R03 AG064106
6 · The paper itself

Abstract

COVID-19 is a severe infectious disease that has claimed >150,000 lives and infected millions in the United States thus far, especially the elderly population. Emerging evidence has shown the virus to cause hemorrhagic and immunologic responses, which impact all organs, including lungs, kidneys, and the brain, as well as extremities. SARS-CoV-2 also affects patients', families', and society's mental health at large. There is growing evidence of re-infection in some patients. The goal of this paper is to provide a comprehensive review of SARS-CoV-2-induced disease, its mechanism of infection, diagnostics, therapeutics, and treatment strategies, while also focusing on less attended aspects by previous studies, including nutritional support, psychological, and rehabilitation of the pandemic and its management. We performed a systematic review of >1,000 articles and included 425 references from online databases, including, PubMed, Google Scholar, and California Baptist University's library. COVID-19 patients go through acute respiratory distress syndrome, cytokine storm, acute hypercoagulable state, and autonomic dysfunction, which must be managed by a multidisciplinary team including nursing, nutrition, and rehabilitation. The elderly population and those who are suffering from Alzheimer's disease and dementia related illnesses seem to be at the higher risk. There are 28 vaccines under development, and new treatment strategies/protocols are being investigated. The future management for COVID-19 should include B-cell and T-cell immunotherapy in combination with emerging prophylaxis. The mental health and illness aspect of COVID-19 are among the most important side effects of this pandemic which requires a national plan for prevention, diagnosis and treatment.

Indexed as

Coronavirus InfectionsPandemicsPneumonia, ViralCOVID-19COVID-19 Drug TreatmentHumansImmunotherapyMental HealthNutritional SupportActemraAlzheimer’s diseaseAvigancoronavirusCOVID-19COVID-19 air filtrationCOVID-19 Alzheimer’s Disease and dementiaCOVID-19 anticoagulantsCOVID-19 antiviralCOVID-19 Clinical manifestationsCOVID-19 complicationsCOVID-19 Convalescent plasmaCOVID-19 diagnosticsCOVID-19 domestic abuseCOVID-19 immunotherapyCOVID-19 Janus Kinase Inhibitor 1 and 2COVID-19 mental disordersCOVID-19 monoclonal antibodiesCOVID-19 Natural Killer Cells and stem cell therapyCOVID-19 Neurological implicationsCOVID-19 NutritionCOVID-19 ophthalmologyCOVID-19 RehabilitationCOVID-19 Risk factors and comorbiditiesCOVID-19 ScreeningCOVID-19 SteroidsCOVID-19 testCOVID-19 VaccinesHydroxychloroquinemental healthNanomedicine for COVID-19RemdesivirSARS-CoV-2SARS-CoV-2 treatment

Identifiers

PMID32925078
PMCPMC7592693
OpenAlexW3085523713

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.