Evidence map›Paper›PMID 32925063›Full record

ArticleJournal of Alzheimer's disease : JAD2020

Future Directions for Dementia Risk Reduction and Prevention Research: An International Research Network on Dementia Prevention Consensus.

Kaarin J Anstey, Ruth Peters, Lidan Zheng, Deborah E Barnes, Carol Brayne, Henry Brodaty, John Chalmers, Linda Clare, Roger A Dixon, Hiroko Dodge and 6 more

Registry-linked trialOpen access · bronzeAbstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05375513 (A Home-based Personalized Multidomain RCT from the Canadian Therapeutic Platform for Multidomain Interventions to Prevent Dementia), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05375513 narecruitingnot on this mapstarted 2023, after this paper: background citation

A Home-based Personalized Multidomain RCT from the Canadian Therapeutic Platform for Multidomain Interventions to Prevent Dementia (CAN-THUMBS UP)

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2023 to 2026Enrolled275ConditionsMild Cognitive ImpairmentArmsPMI@Home, Brain Health Pro
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Umbrella review and Delphi study on modifiable factors for dementia risk reduction.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Pooled it
  2. Trial
  3. Trial
  4. A gradual and sustainable approach to diagnosing sleep and circadian disturbances in dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Association between metabolic syndrome and risk of incident dementia in UK Biobank.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  13. Life-Course Brain Health as a Determinant of Late-Life Mental Health: American Association for Geriatric Psychiatry Expert Panel Recommendations.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023
    Article
  14. Change in physical activity and systolic blood pressure trajectories throughout mid-life and the development of dementia in older age: the HUNT study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2023
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 14 institutions in 6 countries.

Kaarin J AnsteyUNSW Aging Futures Institute, School of Psychology, University of New South Wales, Sydney, NSW, Australia.
Ruth PetersUNSW Aging Futures Institute, School of Psychology, University of New South Wales, Sydney, NSW, Australia.
Lidan ZhengUNSW Aging Futures Institute, School of Psychology, University of New South Wales, Sydney, NSW, Australia.
Deborah E BarnesDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.
Carol BrayneCambridge Public Health, University of Cambridge, Forvie Site, Cambridge, UK.
Henry BrodatyCentre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.
John ChalmersFaculty of Medicine, The George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia.
Linda ClareCollege of Medicine and Health, University of Exeter, St Luke's Campus, Exeter, UK.
Roger A DixonNeuroscience and Mental Health Institute, Department of Psychology, University of Alberta, Edmonton, AB, Canada.
Hiroko DodgeLayton Aging and Alzheimer's Disease Center, Department of Neurology, Oregon Health & Science University, Portland, OR, USA.
Nicola T LautenschlagerAcademic Unit for Psychiatry of Old Age, Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia.
Laura E MiddletonDepartment of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada.
Chengxuan QiuAging Research Center and Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden.
Glenn ReesAlzheimer's Disease International, London, UK.
Suzana ShaharCenter for Healthy Ageing & Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia.
Kristine YaffeDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.
Neuroscience Research Australia · AUUNSW Sydney · AUAlzheimer Disease International · GBKarolinska Institutet · SENational University of Malaysia · MYSan Francisco VA Health Care System · USThe George Institute for Global Health · AUThe Royal Melbourne Hospital · AUUniversity of Alberta · CAUniversity of California, San Francisco · USUniversity of Cambridge · GBUniversity of Exeter · GBUniversity of Michigan–Ann Arbor · USUniversity of Waterloo · CA

Funding

Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Zachary Beattie · 2020 to 2026
$28.6M
Outreach, Recruitment and Education CoreP30AG008017 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KAYE, JEFFREY A · 1990 to 2019
$27.7M
Conversational Engagement as a Means to Delay Onset AD: Phase II Administrative SupplementR01AG051628 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI DODGE, HIROKO HAYAMA · 2016 to 2020
$4.8M
NIA NIH HHS P30 AG008017NIA NIH HHS P30 AG066518NIA NIH HHS R01 AG051628
6 · The paper itself

Abstract

In the past decade a large body of evidence has accumulated on risk factors for dementia, primarily from Europe and North America. Drawing on recent integrative reviews and a consensus workshop, the International Research Network on Dementia Prevention developed a consensus statement on priorities for future research. Significant gaps in geographical location, representativeness, diversity, duration, mechanisms, and research on combinations of risk factors were identified. Future research to inform dementia risk reduction should fill gaps in the evidence base, take a life-course, multi-domain approach, and inform population health approaches that improve the brain-health of whole communities.

Indexed as

Biomedical ResearchRisk Reduction BehaviorConsensusDementiaEuropeHumansNorth AmericaRisk FactorsMulti-domainprimary preventionrisk factorrisk reduction

Identifiers

PMID32925063
PMCPMC7609069
OpenAlexW3086434969

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.