Evidence map›Paper›PMID 32924748›Full record

ArticleJournal of the American Heart Association2020

Contemporary Incidence and Prevalence of Rheumatic Fever and Rheumatic Heart Disease in Australia Using Linked Data: The Case for Policy Change.

Judith M Katzenellenbogen, Daniela Bond-Smith, Rebecca J Seth, Karen Dempsey, Jeffrey Cannon, Ingrid Stacey, Vicki Wade, Nicholas de Klerk, Melanie Greenland, Frank M Sanfilippo and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 123 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Acute rheumatic fever and rheumatic heart disease.Nature reviews. Disease primers · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Streptococcal Serology Reference Intervals in an Australian Pediatric Cohort.Journal of the Pediatric Infectious Diseases Society · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Characterization ofMicroorganisms · 2025
    Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Judith M KatzenellenbogenThe University of Western Australia Perth Australia.
Daniela Bond-SmithThe University of Western Australia Perth Australia.
Rebecca J SethThe University of Western Australia Perth Australia.
Karen DempseyMenzies School of Health ResearchCharles Darwin University Darwin Australia.
Jeffrey CannonTelethon Kids Institute Perth Australia.
Ingrid StaceyThe University of Western Australia Perth Australia.
Vicki WadeMenzies School of Health ResearchCharles Darwin University Darwin Australia.
Nicholas de KlerkThe University of Western Australia Perth Australia.
Melanie GreenlandUniversity of Oxford United Kingdom.
Frank M SanfilippoThe University of Western Australia Perth Australia.
Alex BrownTelethon Kids Institute Perth Australia.
Jonathan R CarapetisTelethon Kids Institute Perth Australia.
Rosemary WyberTelethon Kids Institute Perth Australia.
Lee NedkoffThe University of Western Australia Perth Australia.
Joe HungThe University of Western Australia Perth Australia.
Dawn BessarabThe University of Western Australia Perth Australia.
Anna P RalphMenzies School of Health ResearchCharles Darwin University Darwin Australia.
The University of Western Australia · AUThe Kids Research Institute Australia · AUCharles Darwin University · AUUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background In 2018, the World Health Organization prioritized control of acute rheumatic fever (ARF) and rheumatic heart disease (RHD), including disease surveillance. We developed strategies for estimating contemporary ARF/RHD incidence and prevalence in Australia (2015-2017) by age group, sex, and region for Indigenous and non-Indigenous Australians based on innovative, direct methods. Methods and Results This population-based study used linked administrative data from 5 Australian jurisdictions. A cohort of ARF (age <45 years) and RHD cases (<55 years) were sourced from jurisdictional ARF/RHD registers, surgical registries, and inpatient data. We developed robust methods for epidemiologic case ascertainment for ARF/RHD. We calculated age-specific and age-standardized incidence and prevalence. Age-standardized rate and prevalence ratios compared disease burden between demographic subgroups. Of 1425 ARF episodes, 72.1% were first-ever, 88.8% in Indigenous people and 78.6% were aged <25 years. The age-standardized ARF first-ever rates were 71.9 and 0.60/100 000 for Indigenous and non-Indigenous populations, respectively (age-standardized rate ratio=124.1; 95% CI, 105.2-146.3). The 2017 Global Burden of Disease RHD prevalent counts for Australia (<55 years) underestimate the burden (1518 versus 6156 Australia-wide extrapolated from our study). The Indigenous age-standardized RHD prevalence (666.3/100 000) was 61.4 times higher (95% CI, 59.3-63.5) than non-Indigenous (10.9/100 000). Female RHD prevalence was double that in males. Regions in northern Australia had the highest rates. Conclusions This study provides the most accurate estimates to date of Australian ARF and RHD rates. The high Indigenous burden necessitates urgent government action. Findings suggest RHD may be underestimated in many high-resource settings. The linked data methods outlined here have potential for global applicability.

Indexed as

Health PolicyAdolescentAdultAge FactorsAustraliaChildChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornInformation Storage and RetrievalMaleMiddle AgedPrevalenceAustraliaepidemiologyethnicinequalitieslinked datarheumatic heart disease

Identifiers

PMID32924748
PMCPMC7792417
OpenAlexW3086175621

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.