Evidence map›Paper›PMID 32924016›Full record

ArticleBlood cancer discovery2020

Cytotoxic Therapy-Induced Effects on Both Hematopoietic and Marrow Stromal Cells Promotes Therapy-Related Myeloid Neoplasms.

Angela Stoddart, Jianghong Wang, Anthony A Fernald, Elizabeth M Davis, Camille R Johnson, Chunmei Hu, Jason X Cheng, Megan E McNerney, Michelle M Le Beau

Open access · greenAbstract read
In one paragraph

Article in Blood cancer discovery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 31 citations in OpenAlex.

  1. Genetic influences on haematopoiesis.Nature reviews. Genetics · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Osteoimmunology in bone malignancies: a symphony with evil.Journal of the National Cancer Center · 2024
    Review
  8. Review
  9. CHIP: a clonal odyssey of the bone marrow niche.The Journal of clinical investigation · 2024
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Bone Marrow Microenvironment Involvement in t-MN: Focus on Mesenchymal Stem Cells.Mediterranean journal of hematology and infectious diseases · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Angela StoddartDepartment of Medicine, The University of Chicago, Chicago, Illinois. astoddar@bsd.uchicago.edu.
Jianghong WangDepartment of Medicine, The University of Chicago, Chicago, Illinois.
Anthony A FernaldDepartment of Medicine, The University of Chicago, Chicago, Illinois.
Elizabeth M DavisDepartment of Medicine, The University of Chicago, Chicago, Illinois.
Camille R JohnsonDepartment of Medicine, The University of Chicago, Chicago, Illinois.
Chunmei HuDepartment of Medicine, The University of Chicago, Chicago, Illinois.
Jason X ChengDepartment of Pathology, The University of Chicago, Chicago, Illinois.
Megan E McNerneyDepartment of Pathology, The University of Chicago, Chicago, Illinois.
Michelle M Le BeauDepartment of Medicine, The University of Chicago, Chicago, Illinois.
University of Chicago Medicine Comprehensive Cancer Center

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI CHIEN-MIN KAO · 1985 to 2026
$122.1M
The pathogenesis of chromosome 7q deletions in juvenile myelomonocytic leukemiaR01CA231880 · NCI · UNIVERSITY OF CHICAGO · PI MCNERNEY, MEGAN · 2018 to 2022
$1.8M
Molecular mechanisms of myeloid suppressor genes on chromosome 5R01CA190372 · NCI · UNIVERSITY OF CHICAGO · PI LE BEAU, MICHELLE M · 2015 to 2019
$1.8M
NCI NIH HHS P30 CA014599NCI NIH HHS R01 CA190372NCI NIH HHS R01 CA231880
6 · The paper itself

Abstract

Therapy-related myeloid neoplasms (t-MNs) following treatment with alkylating agents are characterized by a del(5q), complex karyotypes, alterations of

Indexed as

Antineoplastic Agents, AlkylatingBone MarrowLeukemia, MyeloidNeoplasms, Second PrimaryAnimalsChromosome DeletionGenes, p53MiceStromal CellsTumor MicroenvironmentAntineoplastic Agents, Alkylatingdel(5q)mesenchymal stromal cellssenescencetherapy-related myeloid neoplasmsTP53

Identifiers

PMID32924016
PMCPMC7486063
OpenAlexW3016641373

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.