Evidence map›Paper›PMID 32923960›Full record

ReviewVascular biology (Bristol, England)2019

Ghrelin and vascular protection.

James T Pearson, Mikiyasu Shirai, Vijayakumar Sukumaran, Cheng-Kun Du, Hirotsugu Tsuchimochi, Takashi Sonobe, Mark T Waddingham, Rajesh Katare, Daryl O Schwenke

Open access · diamondAbstract readReview
In one paragraph

Review in Vascular biology (Bristol, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. The machinery of healthy vasodilatation: an overview.Pflugers Archiv : European journal of physiology · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Endogenous Vasoactive Peptides and Vascular Aging-Related Diseases.Oxidative medicine and cellular longevity · 2022
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

James T PearsonDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.
Mikiyasu ShiraiDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.
Vijayakumar SukumaranDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.
Cheng-Kun DuDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.
Hirotsugu TsuchimochiDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.
Takashi SonobeDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.
Mark T WaddinghamDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.
Rajesh KatareDepartment of Physiology, HeartOtago, School of Biomedical Sciences University of Otago, Dunedin, New Zealand.
Daryl O SchwenkeDepartment of Physiology, HeartOtago, School of Biomedical Sciences University of Otago, Dunedin, New Zealand.
National Cerebral and Cardiovascular Center · JPUniversity of Otago · NZMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function by maintaining the balance of vasodilator-vasoconstrictor factors, inhibiting inflammatory cytokine production and immune cell recruitment to sites of vascular injury and by promoting angiogenesis.

Indexed as

angiogenesisghrelinGHS-R1ainflammationvasodilation

Identifiers

PMID32923960
PMCPMC7439925
OpenAlexW2972112598

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.