Evidence map›Paper›PMID 32923872›Full record

ArticleJCO precision oncology2020

Pan-Cancer Landscape Analysis Reveals Recurrent

Lucas R Massoth, Yin P Hung, Dora Dias-Santagata, Maristela Onozato, Nikunj Shah, Eric Severson, Daniel Duncan, Brendan J Gillespie, Nathan F Williams, Jeffrey S Ross and 8 more

Open access · hybridAbstract read
In one paragraph

Article in JCO precision oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. NovelCancers · 2025
    Article
  8. Article
  9. Review
  10. Review
  11. The Molecular Landscape of Thymic Epithelial Tumors: A Comprehensive Review.International journal of molecular sciences · 2024
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Thymic Epithelial Tumors: An Evolving Field.Life (Basel, Switzerland) · 2023
    Review
  17. Review
  18. Article
  19. Thymic Carcinomas-A Concise Multidisciplinary Update on Recent Developments From the Thymic Carcinoma Working Group of the International Thymic Malignancy Interest Group.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Lucas R MassothDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Yin P HungDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Dora Dias-SantagataDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Maristela OnozatoDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Nikunj ShahFoundation Medicine, Cambridge, MA.
Eric SeversonFoundation Medicine, Cambridge, MA.
Daniel DuncanFoundation Medicine, Cambridge, MA.
Brendan J GillespieFoundation Medicine, Cambridge, MA.
Nathan F WilliamsDepartment of Mathematical Sciences, University of Texas at Dallas, Dallas, TX.
Jeffrey S RossFoundation Medicine, Cambridge, MA.
Jo-Anne VergilioFoundation Medicine, Cambridge, MA.
Shannon K HarkinsDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Krzysztof GlomskiDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Valentina NardiDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Lawrence R ZukerbergDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Robert P HasserjianDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Abner LouissaintDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Erik A WilliamsFoundation Medicine, Cambridge, MA.
Foundation Medicine (United States)Massachusetts General Hospital · USHarvard University · USSUNY Upstate Medical University · USThe University of Texas at Dallas · US

Funding

Molecular determinants of prognosis in limited-stage follicular lymphomaK23CA184279 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI LOUISSAINT, ABNER · 2014 to 2018
$701k
NCI NIH HHS K23 CA184279
6 · The paper itself

Abstract

purposeThymomas are epithelial neoplasms that represent the most common thymic tumors in adults. These tumors have been shown to harbor a relatively low mutational burden. As a result, there is a lack of genetic alterations that may be used prognostically or targeted therapeutically for this disease. Here, we describe a recurrent gene rearrangement in type B2 + B3 thymomas. PATIENTS AND

methodsA single index case of thymoma was evaluated by an RNA-based solid fusion assay. Separately, tissues from 255,008 unique advanced cancers, including 242 thymomas, were sequenced by hybrid capture-based next-generation DNA sequencing/comprehensive genomic profiling of 186 to 406 genes, including lysine methyltransferase 2A (

resultsWe identified 11 patients with thymomas harboring a gene fusion of

conclusion

Identifiers

PMID32923872
PMCPMC7446345
OpenAlexW3008223363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.