ArticleAmerican journal of ophthalmology case reports2020
Long-term clinical outcomes after Descemet Membrane Endothelial Keratoplasty (DMEK) in Irido-Corneal Endothelial Syndrome.
Article in American journal of ophthalmology case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 8 citations in OpenAlex.
- Descemet membrane endothelial keratoplasty in eyes with glaucoma.Taiwan journal of ophthalmologyReview
- Descemet's membrane endothelial keratoplasty in an eye with iridocorneal endothelial syndrome and rare association of corneal ectasia.Therapeutic advances in ophthalmologyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the long-term clinical outcomes after Descemet Membrane Endothelial Keratoplasty (DMEK) in Irido-Corneal Endothelial Syndrome (ICE). OBSERVATION: Four eyes of four patients diagnosed with ICE syndrome were treated with DMEK. Postoperatively, best corrected visual acuity (BCVA) and central endothelial cell density (ECD) were documented at 6, 12, 24 and 36 months for all the cases. All procedures were uneventful. Average follow-up time was 36 months. BCVA improved in all eyes. Mean BCVA improved significantly from 1.54 ± 0.71 log MAR preoperatively to 0.11 ± 0.14 logMAR at the final follow-up. Average donor ECD was 2895 ± 357 cells/mm
conclusionDMEK is a relatively safe procedure providing favourable clinical outcomes in eyes with ICE syndrome. Since angle closure is progressive in these condition, regular IOP monitoring and glaucoma control is critical for long term survival of the graft. IMPORTANCE: Till date management of ICE syndrome has always been a great challenge due to its varied presentation and complex anatomical abnormalities. Replacing the endothelial cells in an irregular anterior chamber poses additional difficulty. Even well-trained DMEK surgeons find it difficult to appose the Descemet's Membrane (DM) in such a scenario and we in this article provide key surgical tips for successful long term management of these cases.
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