ArticleBiochemistry and biophysics reports2020
Exposure to low temperatures suppresses the production of B-cell activating factor via TLR3 in BEAS-2B cells.
Article in Biochemistry and biophysics reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Impact of airflow stimulation: mild cold airflow is more sensitive to influenza virus infection.Journal of thoracic disease · 2025Article
- Cold waves and fine particulate matter in high-altitude Chinese cities: assessing their interactive impact on outpatient visits for respiratory disease.BMC public health · 2024Article
- SIgA in various pulmonary diseases.European journal of medical research · 2023Review
- Asymmetric impact of temperature on COVID-19 spread in India: Evidence from quantile-on-quantile regression approach.Journal of thermal biology · 2022Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute viral respiratory tract infections (RTIs) are commonly associated with cold weather; however, the mechanism behind this is still unclear. Secretory IgA (sIgA) mainly contributes to the immune response against pathogenic microorganisms in the respiratory tract. Certain pathogen-associated molecular patterns (PAMPs) induce the expression of B-cell activating factor (BAFF) in epithelial cells, macrophages, and dendritic cells. BAFF transforms B cells into plasma cells, which leads to the mass production of immunoglobulins, including IgA, on the mucosal epithelium. However, no studies have described the relationship between cold exposure and BAFF and/or sIgA in RTI. The aim of our study was to determine this relationship
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