Evidence map›Paper›PMID 32923609›Full record

ArticleScience advances2020

A nucleotidyltransferase toxin inhibits growth of

Yiming Cai, Ben Usher, Claude Gutierrez, Anastasia Tolcan, Moise Mansour, Peter C Fineran, Ciarán Condon, Olivier Neyrolles, Pierre Genevaux, Tim R Blower

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 47 citations in OpenAlex.

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  8. Modified DNA substrate selectivity by GmrSD-family Type IV restriction enzyme BrxU.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Yiming CaiLaboratoire de Microbiologie et Génétique Moléculaires, Centre de Biologie Intégrative, Université de Toulouse, CNRS, UPS, 118 route de Narbonne, 31400 Toulouse, France.ORCID 0000-0003-2922-2136
Ben UsherDepartment of Biosciences, Durham University, South Road, Durham DH1 3LE, UK.ORCID 0000-0002-2649-1210
Claude GutierrezInstitut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, 205 route de Narbonne, 31400 Toulouse, France.ORCID 0000-0003-1777-0223
Anastasia TolcanUMR8261 (CNRS, Université de Paris), Institut de Biologie Physico-Chimique, 13 rue Pierre et Marie Curie, 75005 Paris, France.
Moise MansourLaboratoire de Microbiologie et Génétique Moléculaires, Centre de Biologie Intégrative, Université de Toulouse, CNRS, UPS, 118 route de Narbonne, 31400 Toulouse, France.ORCID 0000-0003-1028-6113
Peter C FineranDepartment of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin 9054, New Zealand.ORCID 0000-0002-4639-6704
Ciarán CondonUMR8261 (CNRS, Université de Paris), Institut de Biologie Physico-Chimique, 13 rue Pierre et Marie Curie, 75005 Paris, France.ORCID 0000-0002-2199-9621
Olivier NeyrollesInstitut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, 205 route de Narbonne, 31400 Toulouse, France.ORCID 0000-0003-0047-5885
Pierre GenevauxLaboratoire de Microbiologie et Génétique Moléculaires, Centre de Biologie Intégrative, Université de Toulouse, CNRS, UPS, 118 route de Narbonne, 31400 Toulouse, France.ORCID 0000-0001-7539-3126
Tim R BlowerDepartment of Biosciences, Durham University, South Road, Durham DH1 3LE, UK.ORCID 0000-0002-7390-6458
Centre National de la Recherche Scientifique · FRDurham University · GBUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxin-antitoxin systems are widespread stress-responsive elements, many of whose functions remain largely unknown. Here, we characterize the four DUF1814-family nucleotidyltransferase-like toxins (MenT

Indexed as

Mycobacterium tuberculosisToxin-Antitoxin SystemsTuberculosisBacterial ProteinsHumansNucleotidyltransferasesRNA, TransferBacterial ProteinsNucleotidyltransferasesRNA, Transfer

Identifiers

PMID32923609
PMCPMC7450476
OpenAlexW3035468173

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.