ArticleGlobal pediatric health2020
Minimally Invasive Tissue Sampling in Preterm Deaths: A Validation Study.
Article in Global pediatric health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Bacterial pathogens and antimicrobial resistance patterns in infections associated with stillbirths and under-five deaths in Ethiopia: a post-mortem surveillance study.BMC infectious diseases · 2026Article
- [High diagnostic discrepancy in infectious diseases detected by autopsy].Revista medica del Instituto Mexicano del Seguro Social · 2026Article
- Article
- Exploring minimally invasive tissue sampling as an alternative to conventional autopsy in neonatal deaths.Forensic science, medicine, and pathology · 2026Observational
- Late gestation stillbirth epidemiology: findings from a nationally representative mortality survey of one million population sample in India.BMC pregnancy and childbirth · 2026Article
- Strengthening identification and characterization of causes of perinatal deaths in Kaski district of Nepal (Perinatal MITS Nepal).BMC pregnancy and childbirth · 2025Article
- "Ethiopian journal of health sciences · 2024Article
- Clinicopathological discrepancies in the diagnoses of childhood causes of death in the CHAMPS network: An analysis of antemortem diagnostic inaccuracies.BMJ paediatrics open · 2024Article
- The discrepancy of antemortem clinical diagnosis and postmortem autopsy diagnosis of lung pathologies in under-five deaths and the reasons for discrepancies: a case series analysis.BMC pediatrics · 2024Article
- Provider adherence to clinical care recommendations for infants and children who died in seven low- and middle-income countries in the Child Health and Mortality Prevention Surveillance (CHAMPS) network.EClinicalMedicine · 2023Article
- Pathogens Identified by Minimally Invasive Tissue Sampling in India and Pakistan From Preterm Neonatal Deaths: The PURPOSE Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Observational
- The causes of preterm neonatal deaths in India and Pakistan (PURPOSe): a prospective cohort study.The Lancet. Global health · 2022Article
- Building Capacity and Infrastructure at Hospitals Implementing Minimally Invasive Tissue Sampling: Experience and Lessons Learned From Nepal, Rwanda, and Tanzania.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Factors Associated With Parental Acceptance of Minimally Invasive Tissue Sampling to Identify the Causes of Stillbirth and Neonatal Death.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Cause of Death in Neonates With Neurological Insults in the Neonatal Intensive Care Unit: Insights From A MITS Pilot Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Short Term Outcome and Predictors of Mortality Among Very Low Birth Weight Infants-A Descriptive Study: Authors' Reply.Indian journal of pediatrics · 2021Article
- Validating a Minimally Invasive Tissue Sampling (MITS) Method in Determining Cause of Death in Stillbirths and Neonates.Children (Basel, Switzerland) · 2021Article
- Why parents agree or disagree for minimally invasive tissue sampling (MITS) to identify causes of death in under-five children and stillbirth in North India: a qualitative study.BMC pediatrics · 2021Article
- Prematurity: An Overview and Public Health Impacts of Being Born Too Early.Global pediatric health · 2021Article
Corrections and comments
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Authors and funding
17 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Uncertainty about the causes of neonatal deaths impedes achieving global health targets to reduce mortality. Complete diagnostic autopsy (CDA) is the gold standard to determine cause of death. However, it is often difficult to perform in high-burden, low-income settings. Validations of more feasible methods to determine cause of death are needed. This prospective, multi-center study in Ethiopia assessed the validity of the minimally invasive tissue sampling (MITS) approach to contribute to causes of death in preterm neonates compared to CDA. The MITS and CDA of 105 cases were reviewed. The MITS sampling success for lungs and liver was 100% and 84%, respectively. The kidney and brain had sampling successes of 58% each. MITS showed good agreement with CDA for the diagnosis of hyaline membrane disease (kappa = 0.78), and moderate to substantial agreement for pneumonia and pulmonary hemorrhage (kappa = 0.59 and 0.68, respectively). Even though CDA is the gold standard in identifying the cause of death, we believe that the MITS method can be a useful alternative method in supporting determination of cause of death in low-resource settings.
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