Evidence map›Paper›PMID 32923331›Full record

SynthesisGlobal heart2020

A Systematic Review of the Spectrum of Cardiac Arrhythmias in Sub-Saharan Africa.

Matthew F Yuyun, Aimé Bonny, G André Ng, Karen Sliwa, Andre Pascal Kengne, Ashley Chin, Ana Olga Mocumbi, Marcus Ngantcha, Olujimi A Ajijola, Gene Bukhman

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Global heart, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The competency of nurses in basic life support at district hospitals in Cape Town, South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
    Observational
  5. Review
  6. Article
  7. Observational
  8. Review
  9. Electrical storm in a middle-aged man.Ghana medical journal · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 7 countries.

Matthew F YuyunDepartment of Medicine, Harvard Medical School, Boston, US.
Aimé BonnyDistrict Hospital Bonassama, Douala/University of Douala, CM.
G André NgNational Institute for Health Research Leicester Biomedical Research Centre, Department of Cardiovascular Sciences, University of Leicester, UK.
Karen SliwaHatter Institute for Cardiovascular Research in Africa, University of Cape Town, ZA.
Andre Pascal KengneSouth African Medical Research Council and Department of Medicine, University of Cape Town, ZA.
Ashley ChinThe Cardiac Clinic, Department of Medicine, Groote Schuur Hospital and University of Cape Town, ZA.
Ana Olga MocumbiInstituto Nacional de Saúde and Universidade Eduardo Mondlane, Maputo, MZ.
Marcus NgantchaHomeland Heart Centre, Douala, CM.
Olujimi A AjijolaRonald Reagan UCLA Medical Center Los Angeles, US.
Gene BukhmanDepartment of Medicine, Harvard Medical School, Boston, US.
AstraZeneca (Sweden) · SEUniversity of Cape Town · ZABrigham and Women's Hospital · USEduardo Mondlane University · MZGroote Schuur Hospital · ZANational Institute for Health Research · GBRonald Reagan UCLA Medical Center · USVA Boston Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major structural cardiovascular diseases are associated with cardiac arrhythmias, but their full spectrum remains unknown in sub-Saharan Africa (SSA), which we addressed in this systematic review. Atrial fibrillation/atrial flutter (AF/AFL) prevalence is 16-22% in heart failure, 10-28% in rheumatic heart disease, 3-7% in cardiology admissions, but <1% in the general population. Use of oral anticoagulation is heterogenous (9-79%) across SSA. The epidemiology of sudden cardiac arrest/death is less characterized in SSA. Cardiopulmonary resuscitation is challenging, owing to low awareness and lack of equipment for life-support. About 18% of SSA countries have no cardiac implantable electronic devices services, leaving hundreds of millions of people without any access to treatment for advanced bradyarrhythmias, and implant rates are more than 200-fold lower than in the western world. Management of tachyarrhythmias is largely non-invasive (about 80% AF/AFL via rate-controlled strategy only), as electrophysiological study and catheter ablation centers are almost non-existent in most countries. Highlights: - Atrial fibrillation/flutter prevalence is 16-22% in heart failure, 10-28% in rheumatic heart disease, 3-7% in cardiology admissions, and <1% in the general population in sub-Saharan Africa (SSA).- Rates of oral anticoagulation use for CHA2DS2VASC score ≥2 are very diverse (9-79%) across SSA countries.- Data on sudden cardiac arrest are scant in SSA with low cardiopulmonary resuscitation awareness.- Low rates of cardiac implantable electronic devices insertions and rarity of invasive arrhythmia treatment centers are seen in SSA, relative to the high-income countries.

Indexed as

Africa South of the SaharaArrhythmias, CardiacHumansMorbidityatrial arrhythmiasdefibrillatorpacemakersub-Saharan Africasudden cardiac deathsupraventricular tachycardiaventricular arrhythmias

Identifiers

PMID32923331
PMCPMC7413135
OpenAlexW3023783108

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.