Evidence map›Paper›PMID 32923213›Full record

ArticleCureus2020

Dronedarone-Mediated Acute Hepatic and Renal Toxicity.

Zarak H Khan, Kashif Mukhtar, Munis M Ahmed, Syeda Ramsha Zaidi, Randa Abd Algayoum

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Zarak H KhanInternal Medicine, St. Mary Mercy Hospital, Livonia, USA.
Kashif MukhtarInternal Medicine, St. Mary Mercy Hospital, Livonia, USA.
Munis M AhmedInternal Medicine, St. Mary Mercy Hospital, Livonia, USA.
Syeda Ramsha ZaidiInternal Medicine, St. Mary Mercy Hospital, Livonia, USA.
Randa Abd AlgayoumInternal Medicine, St. Mary Mercy Hospital, Livonia, USA.
St. Mary Mercy Livonia · USMercy Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dronedarone, a drug similar in chemical properties to amiodarone, was designed to have similar pharmacodynamic properties as amiodarone with fewer side effects. Although there have been cases of chronic liver enzyme elevation with dronedarone, only a few cases have been reported in literature where it has led to rapid onset of liver failure. We present the case of an 86-year-old male who developed acute liver failure concomitantly with acute kidney failure after he was started on dronedarone therapy.

Indexed as

acute liver failureacute renal injurydronedarone

Identifiers

PMID32923213
PMCPMC7478565
OpenAlexW3048059104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.