Evidence map›Paper›PMID 32923164›Full record

ArticleOncoimmunology2020

Immune vulnerability of ovarian cancer stem-like cells due to low CD47 expression is protected by surrounding bulk tumor cells.

Chih-Long Chang, Chao-Chih Wu, Yun-Ting Hsu, Yi-Chiung Hsu

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Deciphering the role of CD47 in cancer immunotherapy.Journal of advanced research · 2024
    Review
  4. The biological roles of CD47 in ovarian cancer progression.Cancer immunology, immunotherapy : CII · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Review
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chih-Long ChangDepartmental of Medical Research, MacKay Memorial Hospital, New Taipei City, Taiwan.ORCID 0000-0003-3981-9366
Chao-Chih WuDepartmental of Medical Research, MacKay Memorial Hospital, New Taipei City, Taiwan.ORCID 0000-0001-7280-2342
Yun-Ting HsuDepartmental of Medical Research, MacKay Memorial Hospital, New Taipei City, Taiwan.
Yi-Chiung HsuDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan.ORCID 0000-0002-8712-8714
Mackay Memorial Hospital · TWNational Central University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrence of advanced epithelial ovarian cancer is common despite optimal surgical debulking and initial favorable responses to chemotherapy. Evidences suggest that cancer stem cells (CSCs) have inherent resistance to conventional therapies such as chemotherapy and play a decisive role in cancer recurrence. Cancer stem cells are also believed to be able to evade immunological attack. However, this study showed a different scenario in which cancer stem-like cells are more vulnerable to immunosurveillance. Our study demonstrated that isolated murine cancer stem-like cells, stem cell antigen (SCA)-1

Indexed as

CD47 AntigenOvarian NeoplasmsAnimalsApoptosisCell Line, TumorFemaleHumansMiceNeoplasm Recurrence, LocalNeoplastic Stem CellsTumor MicroenvironmentCD47 AntigenCD47 protein, humanCd47 protein, mouseCancer stem cellCD47ovarian cancertumor microenvironment

Identifiers

PMID32923164
PMCPMC7458642
OpenAlexW3080246707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.