Evidence map›Paper›PMID 32923117›Full record

ArticleOncoimmunology2020

IL-17 suppresses the therapeutic activity of cancer vaccines through the inhibition of CD8

Gilles Dadaglio, Catherine Fayolle, Marine Oberkampf, Alexandre Tang, Francesc Rudilla, Isabelle Couillin, Eirik A Torheim, Pierre Rosenbaum, Claude Leclerc

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Systemic treatment of immune checkpoint inhibitor-induced psoriasis: Inference-based guidance.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Innate Lymphoid Cells.Advances in experimental medicine and biology · 2025
    Review
  7. Article
  8. LinkingAntibiotics (Basel, Switzerland) · 2024
    Review
  9. T cells in health and disease.Signal transduction and targeted therapy · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. LncRNAs Target Ferroptosis-Related Genes and Impair Activation of CD4Frontiers in cell and developmental biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Gilles DadaglioInstitut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Paris, France.
Catherine FayolleInstitut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Paris, France.
Marine OberkampfInstitut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Paris, France.
Alexandre TangInstitut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Paris, France.ORCID 0000-0002-8981-1226
Francesc RudillaInstitut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Paris, France.
Isabelle CouillinMolecular and Experimental Immunology and Neurogenetics, NEM, CNRS, UMR7355 INEM, CNRS and University of Orléans, Orléans, France.
Eirik A TorheimInstitut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Paris, France.
Pierre RosenbaumInstitut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Paris, France.
Claude LeclercInstitut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Paris, France.ORCID 0000-0003-2140-0540
Inserm · FRUniversité d'Orléans · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antitumor immunity is mediated by Th1 CD4

Indexed as

Cancer VaccinesCD8-Positive T-LymphocytesInterleukin-17NeoplasmsAdjuvants, ImmunologicAnimalsFemaleMelanoma, ExperimentalMiceMice, Inbred C57BLTh1 CellsAdjuvants, ImmunologicCancer VaccinesInterleukin-17cytotoxic T cellsIL-17neutrophilsTh17 cellsTumor immunity

Identifiers

PMID32923117
PMCPMC7458594
OpenAlexW3025138115

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.