Evidence map›Paper›PMID 32923109›Full record

ArticleOncoimmunology2019

Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer.

Brett J Hos, Marcel G M Camps, Jitske van den Bulk, Elena Tondini, Thomas C van den Ende, Dina Ruano, Kees Franken, George M C Janssen, Arnoud Ru, Dmitri V Filippov and 4 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
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  4. Increasing intrinsic protein disorder improves CD8+ immunogenicity for a SARS CoV2 vaccine candidate antigen.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
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  12. Stem-like PD-1Journal for immunotherapy of cancer · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. A Framework for Comparing Mouse Neoantigen Immunogenicity.bioRxiv : the preprint server for biology · 2026
    Article
  19. Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Brett J HosLeiden University Medical Center, Immunohematology and Blood Transfusion, Leiden, The Netherlands.ORCID 0000-0002-1158-5142
Marcel G M CampsLeiden University Medical Center, Immunohematology and Blood Transfusion, Leiden, The Netherlands.
Jitske van den BulkLeiden University Medical Center, Pathology, Leiden, The Netherlands.
Elena TondiniLeiden University Medical Center, Immunohematology and Blood Transfusion, Leiden, The Netherlands.ORCID 0000-0003-2915-337X
Thomas C van den EndeLeiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
Dina RuanoLeiden University Medical Center, Pathology, Leiden, The Netherlands.
Kees FrankenLeiden University Medical Center, Immunohematology and Blood Transfusion, Leiden, The Netherlands.
George M C JanssenLeiden University Medical Center, Center for Proteomics & Metabolomics, Leiden, The Netherlands.
Arnoud RuLeiden University Medical Center, Center for Proteomics & Metabolomics, Leiden, The Netherlands.
Dmitri V FilippovLeiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
Ramon ArensLeiden University Medical Center, Immunohematology and Blood Transfusion, Leiden, The Netherlands.ORCID 0000-0001-5058-4110
Peter A van VeelenLeiden University Medical Center, Center for Proteomics & Metabolomics, Leiden, The Netherlands.
Noel MirandaLeiden University Medical Center, Pathology, Leiden, The Netherlands.
Ferry OssendorpLeiden University Medical Center, Immunohematology and Blood Transfusion, Leiden, The Netherlands.ORCID 0000-0001-9730-7954
Leiden University Medical Center · NLLeiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The murine MC-38 colorectal cancer model is a commonly used model for cancer with high mutational burden, which is sensitive for immune checkpoint immunotherapy. We set out to analyze endogenous CD8

Indexed as

CD8-Positive T-LymphocytesColorectal NeoplasmsAnimalsEpitopesHistocompatibility Antigens Class IMicePeptidesEpitopesHistocompatibility Antigens Class IPeptidescheckpointimmunotherapyNeoantigenPD-L1vaccinationwhole exome sequencing

Identifiers

PMID32923109
PMCPMC7458608
OpenAlexW2981190097

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.