ArticleAmerican journal of blood research2020
Prognostic significance of CD56 and CD7 in acute myeloid leukaemia and their outcome.
Article in American journal of blood research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Decoding Prognostic Signatures in Brain Metastatic Non-Small-Cell Lung Cancer via Integrated Multi-Omics and Network Analysis.International journal of molecular sciences · 2026Article
- Allo-HSCT Might Improve Long-Term Survival in Patients with CD56-Positive AML.Journal of blood medicine · 2026Article
- CD56 on immune and tumor cells: what is known and beyond?Clinical and experimental immunology · 2025Review
- Recent advances of chimeric antigen receptor T-cell therapy for acute myeloid leukemia.Frontiers in immunology · 2025Review
- Frequency and Prognostic Impact of Aberrant Antigens Expression among Egyptian Adult Acute Leukemia.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Prognostic value of lymphoid marker CD7 expression in acute myeloid leukemia patients undergoing allogeneic hematopoietic cell transplantation in first morphological complete remission.International journal of hematology · 2021Article
- DNAM-1/CD226 is functionally expressed on acute myeloid leukemia (AML) cells and is associated with favorable prognosis.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe expression of CD7 and CD56 in Acute Myeloid Leukaemia was considered to be a poor prognostic factor for overall survival, complete remission but the result were limited and more prognostic parameter need to study. The importance of validating new prognostic parameters in acute myeloid leukaemia was the reason to investigate the prognostic significance of CD7 and CD56. MATERIAL AND
methodsStudy involving patients who had newly diagnosed AML. Imunophenotyping was carried out at diagnosis and after induction therapy also compared with molecular and cytogenetics studies. End points were the leukaemia free survival, relapse-free survival, and overall survival.
resultAll 87 patients that were included in the study were divided into 4 groups based on expression of CD56 and CD7 as Group 1 (CD7+, CD56+), group 2 (CD7-, CD56+), group 3 (CD7+, CD56-) and group 4 (CD7-, CD56-) and were compared clinically and immunophenotypically. The clinical parameters that were correlated were age, sex, LFS (leukaemia free survival), Overall survival (OS) and Relapse Free survival (RFS) and were followed up with MRD at day 30 along with Molecular abnormalities and cytogenetic karyotyping.
conclusionThe study data suggest that prognostic significance of CD7 and CD56 expression in patients of acute myeloid leukaemia could be indicative of poor prognosis as it was also associated with the adverse prognostic parameter (Minimal Residual Disease, high risk, shorter overall survival).
Indexed as
Identifiers
32923090PMC7486483W3085235036What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.