ArticleBiomedical optics express2020
Image reconstruction for novel time domain near infrared optical tomography: towards clinical applications.
Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Non-contact Oxygenation Assessment of Biological Tissues Based on a Time-of-Flight Method.Advances in experimental medicine and biology · 2026Article
- Development of a statistically standardized optical digital wrist model through integrated MRI-diffuse optical imaging methodology.Journal of biomedical optics · 2025Article
- Using spectral derivatives to remove the influence of hair on optical images of the static absorbing properties of tissue-like turbid media.Neurophotonics · 2024Article
- Imaging Deep Haemorrhage and Ischaemia in Preterm Infants' Heads with Time-Domain Near-Infrared Optical Tomography: Phantom Study.Advances in experimental medicine and biology · 2024Article
- Fabrication of Tuneable Tissue-Mimicking Phantom for Optical Methods.Advances in experimental medicine and biology · 2024Article
- Imaging Cerebral Blood Vessels Using Near-Infrared Optical Tomography: A Simulation Study.Advances in experimental medicine and biology · 2023Article
- Image Reconstruction Using Deep Learning for Near-Infrared Optical Tomography: Generalization Assessment.Advances in experimental medicine and biology · 2023Article
- Time Domain Near-Infrared Optical Tomography Utilizing Full Temporal Data: A Simulation Study.Advances in experimental medicine and biology · 2023Article
- Resolution and penetration depth of reflection-mode time-domain near infrared optical tomography using a ToF SPAD camera.Biomedical optics express · 2022Article
- Development and Validation of Robust and Cost-Effective Liquid Heterogeneous Phantom for Time Domain Near-Infrared Optical Tomography.Advances in experimental medicine and biology · 2022Article
- 2.5 Hz sample rate time-domain near-infrared optical tomography based on SPAD-camera image tissue hemodynamics.Biomedical optics express · 2022Article
- Dynamic time domain near-infrared optical tomography based on a SPAD camera.Biomedical optics express · 2020Article
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Authors and funding
7 authors.
Funding
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Abstract
Near infrared optical tomography (NIROT) is an emerging modality that enables imaging the oxygenation of tissue, which is a biomarker of tremendous clinical relevance. Measuring in reflectance is usually required when NIROT is applied in clinical scenarios. Single photon avalanche diode (SPAD) array technology provides a compact solution for time domain (TD) NIROT to gain huge temporal and spatial information. This makes it possible to image complex structures in tissue. The main aim of this paper is to validate the wavelength normalization method for our new TD NIROT experimentally by exposing it to a particularly difficult challenge: the recovery of two inclusions at different depths. The proposed reconstruction algorithm aims to tackle systematic errors and other artifacts with known wavelength-dependent relation. We validated the device and reconstruction method experimentally on a silicone phantom with two inclusions: one at depth of 10 mm and the other at 15 mm. Despite this tough challenge for reflectance NIROT, the system was able to localize both inclusions accurately.
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