ArticleBiomedical optics express2020
Characterizing dynamic cerebral vascular reactivity using a hybrid system combining time-resolved near-infrared and diffuse correlation spectroscopy.
Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Full-head Coverage Multi-channel Time-resolved Functional Near Infrared Spectroscopy for Early Detection and Prevention of Perioperative Brain Injury
Cerebral Hemodynamic and Metabolic Responses to Anesthesia and Vasopressors in Adult Surgery: A 2x2 Factorial Design Randomized Controlled Trial With Light-based Neuromonitoring (CHEM-FACT Study)
Who cites it
26 citing papers in PubMed, 38 citations in OpenAlex.
- Dynamic response of cerebral blood flow to insulin-induced hypoglycemia.Scientific reports · 2020Trial
- Toward comprehensive multimodal neuromonitoring of surrogates of cerebral autoregulation in traumatic brain injury: insights from a hyperventilation protocol.Neurophotonics · 2026Article
- MW-FlexNIRS: wearable, low-cost, LED-based, multi-wavelength NIRS oximeter for cytochrome c oxidase recovery in neonates.Biomedical optics express · 2026Article
- Reproducibility of a time-resolved NIRS, multidistance diffuse correlation spectroscopy system: towards noninvasive longitudinal neuromonitoring.Neurophotonics · 2026Article
- "hDOS": an automated hybrid diffuse optical device for real-time noninvasive tissue monitoring: precision andJournal of biomedical optics · 2025Article
- All-optics technique for monitoring absolute cerebral blood flow: validation against magnetic resonance imaging perfusion.Neurophotonics · 2024Article
- Non-invasive optical and laboratory hematologic biomarkers correlate in patients with sickle cell disease.Biomedical optics express · 2024Article
- Chassis-based fiber-coupled optical probe design for reproducible quantitative diffuse optical spectroscopy measurements.PloS one · 2024Article
- Depth-selective method for time-domain diffuse reflectance measurements: validation study of the dual subtraction technique.Biomedical optics express · 2023Article
- Characterization of cerebral macro- and microvascular hemodynamics during transient hypotension.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Portable, high speed blood flow measurements enabled by long wavelength, interferometric diffuse correlation spectroscopy (LW-iDCS).Scientific reports · 2023Article
- Agreement in cerebrovascular reactivity assessed with diffuse correlation spectroscopy across experimental paradigms improves with short separation regression.Neurophotonics · 2023Article
- Using depth-enhanced diffuse correlation spectroscopy and near-infrared spectroscopy to isolate cerebral hemodynamics during transient hypotension.Neurophotonics · 2023Article
- Fast estimation of adult cerebral blood content and oxygenation with hyperspectral time-resolved near-infrared spectroscopy.Frontiers in neuroscience · 2023Article
- Assessing the Sensitivity of Multi-Distance Hyperspectral NIRS to Changes in the Oxidation State of Cytochrome C Oxidase in the Brain.Metabolites · 2022Article
- Optical imaging and spectroscopy for the study of the human brain: status report.Neurophotonics · 2022Article
- Assessing the relationship between the cerebral metabolic rate of oxygen and the oxidation state of cytochrome-c-oxidase.Neurophotonics · 2022Article
- Assessing cerebral blood flow, oxygenation and cytochrome c oxidase stability in preterm infants during the first 3 days after birth.Scientific reports · 2022Article
- Study of cerebrovascular reactivity to hypercapnia by imaging photoplethysmography to develop a method for intraoperative assessment of the brain functional reserve.Biomedical optics express · 2022Article
- Performance assessment of laser sources for time-domain diffuse correlation spectroscopy.Biomedical optics express · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study presents the characterization of dynamic cerebrovascular reactivity (CVR) in healthy adults by a hybrid optical system combining time-resolved (TR) near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS). Blood flow and oxygenation (oxy- and deoxy-hemoglobin) responses to a step hypercapnic challenge were recorded to characterize dynamic and static components of CVR. Data were acquired at short and long source-detector separations (
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.