Evidence map›Paper›PMID 32923053›Full record

ArticleBiomedical optics express2020

Spatial scanning of a sample with two-dimensional angle-resolved low-coherence interferometry for analysis of anisotropic scatterers.

Ge Song, Zachary A Steelman, Wesley Kendall, Han Sang Park, Adam Wax

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ge SongDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Zachary A SteelmanDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Wesley KendallDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Han Sang ParkDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Adam WaxDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.

Funding

Novel Coherence Imaging to Evaluate the Health of the Cervical EpitheliumR01CA167421 · NCI · DUKE UNIVERSITY · PI WAX, ADAM · 2014 to 2018
$3.0M
Advanced a/LCI systems for improved clinical utilityR01CA210544 · NCI · DUKE UNIVERSITY · PI SHAHEEN, NICHOLAS J, WAX, ADAM · 2017 to 2021
$2.7M
Coherent light scattering for early detection of Alzheimer's diseaseR21AG056245 · NIA · DUKE UNIVERSITY · PI WAX, ADAM · 2017 to 2018
$424k
High throughput cell screening for toxic metal exposureR21ES029791 · NIEHS · DUKE UNIVERSITY · PI WAX, ADAM · 2018 to 2019
$403k
NCI NIH HHS R01 CA167421NCI NIH HHS R01 CA210544NIA NIH HHS R21 AG056245NIEHS NIH HHS R21 ES029791
6 · The paper itself

Abstract

Angle-resolved low-coherence interferometry (a/LCI) measures depth-resolved angular scattering for cell nuclear morphology analysis. 2D a/LCI, developed to collect across two scattering planes, is currently limited by the lack of spatial scanning. Here we demonstrate 2D a/LCI scanning across a three-dimensional volume using an image rotation scheme and a scanning mirror. Validation using various optical phantoms demonstrated excellent scatterer size determination over a 7.5 mm linear range, for a total accessible area of ∼44 mm

Identifiers

PMID32923053
PMCPMC7449733

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.