ArticleJournal of pharmaceutical analysis2020
Comparative pharmacokinetics of six major compounds in normal and insomnia rats after oral administration of Ziziphi Spinosae Semen aqueous extract.
Article in Journal of pharmaceutical analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 46 citations in OpenAlex.
- Metabolic Profile and Dynamic Characteristics of Ziziphi Spinosae Semen Flavonoids During Biotransformation and Their Effect on Human Gut Microbiota In Vitro.Foods (Basel, Switzerland) · 2026Article
- Integrating 3D Chromatography With Orbitrap Mass Spectrometry to Profile the Chemical Constituents in JTTZ Formula and Investigate Plasma Pharmacokinetic Changes in Obese Rats.Phytochemical analysis : PCA · 2026Article
- Article
- Spinosin: A Critical Updated Review on Pharmacology, Pharmacokinetics, Toxicity and Translational Bottlenecks.Molecules (Basel, Switzerland) · 2026Review
- Impact of Harvest Timing and Stir-Frying on the Bioactive Compounds, Bioactivities, and Flavor ofPlants (Basel, Switzerland) · 2026Article
- Traditional Chinese medicine on epilepsy: focus on N-methyl-D-aspartate receptors and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.Medical review (2021) · 2025Review
- Analysis of Components in Ziziphi Spinosae Semen Before and After Processing Based on Targeted and Untargeted Metabolomics.Foods (Basel, Switzerland) · 2025Article
- Analysis of metabolites and metabolic pathways of troponin activator in rats using UHPLC-MS.Analytical and bioanalytical chemistry · 2025Article
- Matrix-assisted laser desorption/ionization mass spectrometry imaging analysis revealed the spatial distribution of metabolites duringFrontiers in plant science · 2025Article
- Research progress on the effect of medicine and food homology resources for sleep improvement.Heliyon · 2024Review
- Article
- Spatial distribution of metabolites in processing Ziziphi Spinosae Semen as revealed by matrix-assisted laser desorption/ionization mass spectrometry imaging.Scientific reports · 2024Article
- A Combination of Magnoflorine and Spinosin Improves the Antidepressant effects on CUMS Mouse Model.Current drug metabolism · 2024Article
- Quality evaluation methods of chinese medicine based on scientific supervision: recent research progress and prospects.Chinese medicine · 2023Review
- Integrating animal experiments, mass spectrometry and network-based approach to reveal the sleep-improving effects of Ziziphi Spinosae Semen and γ-aminobutyric acid mixture.Chinese medicine · 2023Article
- Efficacy of electroacupuncture stimulating Shenmen (HT7), Baihui (GV20), Sanyinjiao (SP6) on spatial learning and memory deficits in rats with insomnia induced by para-chlorophenylalanine: a single acupoint combined acupoints.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023Article
- Triterpenoids in Jujube: A Review of Composition, Content Diversity, Pharmacological Effects, Synthetic Pathway, and Variation during Domestication.Plants (Basel, Switzerland) · 2023Review
- The pharmacology, pharmacokinetics, and toxicity of spinosin: A mini review.Frontiers in pharmacology · 2022Review
- Gut microbiota-generated short-chain fatty acids are involved in para-chlorophenylalanine-induced cognitive disorders.Frontiers in microbiology · 2022Article
- Tissue Distribution, Excretion, and Interaction With Human Serum Albumin of Total Bioflavonoid Extract FromFrontiers in pharmacology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ziziphi Spinosae Semen (ZSS), a traditional Chinese medicine, is used in clinics for the treatment of insomnia in China and other Asian countries. Herein, we described for the first time a comparative pharmacokinetics study of the six major compounds of ZSS in normal control (NC) and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.