Evidence map›Paper›PMID 32922949›Full record

ArticleChinese neurosurgical journal2020

Risk factors for the incidence of apoplexy in pituitary adenoma: a single-center study from southwestern China.

Yao Li, Yuan Qian, Yisheng Qiao, Xiaoxiang Chen, Jiaotian Xu, Chao Zhang, Wei Wang, Junjun Li, Xingli Deng

Open access · diamondAbstract read
In one paragraph

Article in Chinese neurosurgical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pituitary Apoplexy Precipitated by Non-Cranial Surgeries: An Institutional Experience.Journal of neurological surgery. Part B, Skull base · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Revisiting Pituitary Apoplexy.Journal of the Endocrine Society · 2022
    Review
  8. Pituitary Apoplexy: Risk Factors and Underlying Molecular Mechanisms.International journal of molecular sciences · 2022
    Review
  9. Pituitary apoplexy: An emergent and potential life-threatening complication of pituitary adenomas.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yao LiDepartment of Neurological Surgery, 1st Affiliated Hospital of Kunming Medical University, Kunming, China.
Yuan QianYunnan Key Laboratory of Laboratory Medicine, Yunnan Engineering Technology Center of Digestive disease, 1st Affiliated Hospital of Kunming Medical University, Kunming, China.
Yisheng QiaoDepartment of Neurological Surgery, 1st Affiliated Hospital of Kunming Medical University, Kunming, China.
Xiaoxiang ChenDepartment of Neurological Surgery, 1st Affiliated Hospital of Kunming Medical University, Kunming, China.
Jiaotian XuDepartment of Neurological Surgery, 1st Affiliated Hospital of Kunming Medical University, Kunming, China.
Chao ZhangDepartment of Neurological Surgery, 1st Affiliated Hospital of Kunming Medical University, Kunming, China.
Wei WangDepartment of Neurological Surgery, 1st Affiliated Hospital of Kunming Medical University, Kunming, China.
Junjun LiDepartment of Neurological Surgery, 1st Affiliated Hospital of Kunming Medical University, Kunming, China.
Xingli DengDepartment of Neurological Surgery, 1st Affiliated Hospital of Kunming Medical University, Kunming, China.ORCID 0000-0003-1331-5549
Kunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the incidence and clinical manifestations of pituitary apoplexy were reported by a few researches, the results are not consistent. This study aimed to explore the risk factors associated with an incidence of apoplexy in pituitary adenomas.

methodsThe clinical information of 843 patients with pituitary adenoma from the Department of Neurological Surgery, 1st Affiliated Hospital of Kunming Medical University, was reviewed. The incidence, clinical manifestation, and potential risk factors for pituitary apoplexy were analyzed by a case-control study.

resultsIn total, 121 patients (14.4%) with macroadenoma were suffered from pituitary apoplexy. Headache, vomiting, and visual impairment are the top 3 symptoms for the pituitary apoplexy.Logistic regression results showed that the hypertension(hypertension vs non-hypertension OR = 2.765, 95%CI:1.41~5.416), tumor type (negative staining vs. positive staining, OR = 1.501, 95%CI:1.248~5.235), and tumor size (diameter > 2 cm vs. diameter ≤ 2 cm, OR = 3.952, 95%CI:2.211~7.053) are independent factors associated with pituitary apoplexy.

conclusionOur results indicate that the risk factors for the incidence of pituitary apoplexy depend mainly on properties of the tumor itself (tumor size and pathologic type) and the blood pressure of patients.

Indexed as

Pituitary adenomaPituitary apoplexyRisk factors

Identifiers

PMID32922949
PMCPMC7398194
OpenAlexW3041460536

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.