Evidence map›Paper›PMID 32922942›Full record

ArticleChinese neurosurgical journal2020

Aggravated pulmonary injury after subarachnoid hemorrhage in PDGF-B

Pengyu Pan, Jie Qu, Qiang Li, Rongwei Li, Yang Yang, Shilun Zuo, Xin Liu, Hua Feng, Yujie Chen

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chinese neurosurgical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Pengyu PanDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038 China.
Jie QuDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038 China.
Qiang LiDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038 China.
Rongwei LiDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038 China.
Yang YangDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038 China.
Shilun ZuoDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038 China.
Xin LiuDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038 China.
Hua FengDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038 China.
Yujie ChenDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038 China.
Army Medical University · CNSouthwest Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent advances in surgical and neuroprotective strategies could effectively manage the pathophysiological progression of subarachnoid hemorrhage (SAH). However, pulmonary dysfunction frequently occurs in SAH patients with an increased risk of unsatisfactory outcomes. Based on the similar microvascular structures in the blood-air barrier and blood-brain barrier and possible brain-lung crosstalks, we believe that pericytes may be involved in both neurological and pulmonary dysfunction after SAH.

methodsIn our experiments, platelet-derived growth factor B (PDGF-B) retention motif knockout (PDGF-B

resultsWe found that neonatal PDGF-B

conclusionsThese results suggested pulmonary dysfunction after SAH and the pivotal role of PDGF-B signaling for the pathophysiological process and future therapeutic targets of pulmonary injury treatment after SAH. Further studies are needed for pathophysiological investigations and translational studies on pulmonary injuries after SAH.

Indexed as

Lung-specific surfactant proteinPlatelet-derived growth factor BPulmonary injurySubarachnoid hemorrhage

Identifiers

PMID32922942
PMCPMC7398237
OpenAlexW3030248632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.