Evidence map›Paper›PMID 32922885›Full record

ArticleChinese neurosurgical journal2018

HOXC8: a predictive glioma biomarker that induces epithelia-mesenchymal transition.

Tingyu Liang, Xiaoxuan Wang, Peiliang Li, Yang Cao, Enshan Feng, Gan You

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chinese neurosurgical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tingyu Liang *Department of Neurosurgery, Beijing Ditan Hospital, Capital Medical University, Beijing, 100020 China.
Xiaoxuan Wang *Capital Medical University, Beijing, 100050 China.
Peiliang LiDepartment of Neurosurgery, Beijing Ditan Hospital, Capital Medical University, Beijing, 100020 China.
Yang CaoDepartment of Neurosurgery, Beijing Ditan Hospital, Capital Medical University, Beijing, 100020 China.
Enshan FengDepartment of Neurosurgery, Beijing Ditan Hospital, Capital Medical University, Beijing, 100020 China.
Gan YouDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 6 TiantanXili, Dongcheng District, Beijing, 100050 China.
Capital Medical University · CNBeijing Ditan Hospital · CNBeijing Institute of Neurosurgery · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe transcription factor Homeobox C8 (

methodBased on the Chinese Glioma Genome Atlas (

resultsPatients with higher HOXC8 levels showed poorer prognosis. DAVID analysis results indicated that HOXC8 was related to cell cycle, cell adhesion and immune response. In U251 and LN229 glioma cells treated with small interfering RNA for HOXC8 (

conclusionHOXC8 may play an important role in glioma proliferation, migration and invasion. These findings indicated that HOXC8 may constitute a novel target for glioma treatment.

Indexed as

Cell cycleEMTHOXC8InvasionMigration

Identifiers

PMID32922885
PMCPMC7398260
OpenAlexW2892033580

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.