ArticleLight, science & applications2020
Multifocal structured illumination optoacoustic microscopy.
Article in Light, science & applications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Optoacoustic brain imaging: A systematic review and field mapping.Photoacoustics · 2026Article
- Multiplexed optoacoustic tracking and magnetic actuation of labeled blood cells in living mice.Science advances · 2026Article
- Multifocal Optical-Resolution Photoacoustic Microscopy With a Masked Single-Element Transducer.IEEE transactions on medical imaging · 2026Article
- Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- A cortex-wide multimodal microscope for simultaneous CaNature communications · 2025Article
- Non-invasive large-scale imaging of concurrent neuronal, astrocytic, and hemodynamic activity with hybrid multiplexed fluorescence and magnetic resonance imaging (HyFMRI).Light, science & applications · 2025Article
- A comprehensive review of high-performance photoacoustic microscopy systems.Photoacoustics · 2025Review
- Wavelength-time-division multiplexed fiber-optic sensor array for wide-field photoacoustic microscopy.Photoacoustics · 2025Article
- Sound Out the Deep Clarity: Super-Resolution Photoacoustic Imaging at Depths.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024Review
- Deep learning-enabled detection of rare circulating tumor cell clusters in whole blood using label-free, flow cytometry.Lab on a chip · 2024Article
- High speed innovations in photoacoustic microscopy.Npj imaging · 2024Review
- Deep optoacoustic localization microangiography of ischemic stroke in mice.Nature communications · 2023Article
- Generation and Modulation of Controllable Multi-Focus Array Based on Phase Segmentation.Micromachines · 2022Article
- Deep learning facilitates fully automated brain image registration of optoacoustic tomography and magnetic resonance imaging.Biomedical optics express · 2022Article
- Non-invasive longitudinal imaging of VEGF-induced microvascular alterations in skin wounds.Theranostics · 2022Article
- High-speed photoacoustic microscopy: A review dedicated on light sources.Photoacoustics · 2021Article
- Emerging imaging methods to study whole-brain function in rodent models.Translational psychiatry · 2021Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optoacoustic (OA) imaging has the capacity to effectively bridge the gap between macroscopic and microscopic realms in biological imaging. High-resolution OA microscopy has so far been performed via point-by-point scanning with a focused laser beam, thus greatly restricting the achievable imaging speed and/or field of view. Herein we introduce multifocal structured illumination OA microscopy (MSIOAM) that attains real-time 3D imaging speeds. For this purpose, the excitation laser beam is shaped to a grid of focused spots at the tissue surface by means of a beamsplitting diffraction grating and a condenser and is then scanned with an acousto-optic deflector operating at kHz rates. In both phantom and in vivo mouse experiments, a 10 mm wide volumetric field of view was imaged with 15 Hz frame rate at 28 μm spatial resolution. The proposed method is expected to greatly aid in biological investigations of dynamic functional, kinetic, and metabolic processes across multiple scales.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.