ArticleInternational journal of clinical and experimental pathology2020
A DNA quantitative analysis of lung cancer cells with different pathological types from bronchial brush specimens and its clinical significance.
Article in International journal of clinical and experimental pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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8 authors.
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Abstract
objectiveTo explore the significance of a DNA quantitative analysis of lung cancer cells with different pathological types taken from bronchial brush specimens and its relationship with the clinicopathological features.
methods903 bronchial brush cytological specimens taken in the Cytology Department of the Fourth Hospital of Hebei Medical University were collected from March 2017 to December 2019 and divided into three groups: the squamous carcinoma (SC) group, the adenocarcinoma (AC) group, and the small-cell carcinoma (SCC) group. The maximum DNA index (DI) value, the percentage of cells with a DI larger than 2.5, the mean DI, and the peaks of the aneuploid cells of the three groups were compared. A single factor analysis was used to analyze the relationship between the DNA content, aneuploidy, and the clinico pathological features of the patients who had surgery.
resultsThe peaks of the aneuploid cells in the SC group, the AC group, and the SCC group had no significant differences (
conclusionThe reason why the DNA content of small-cell lung cancer is lower than SC and AC remains to be further studied.
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32922607PMC7476939What OpenQuestion holds
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