Evidence map›Paper›PMID 32922596›Full record

ArticleInternational journal of clinical and experimental pathology2020

DLEU2 participates in lymphovascular invasion and inhibits cervical cancer cell proliferation, migration, and invasion.

Hanqun Zhang, Xiaohu Wang, Qiuning Zhang, Yan Ma, Zi Wang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Deleted in lymphocytic leukemia 2 (DLEU2): a possible biomarker that holds promise for future diagnosis and treatment of cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Hanqun ZhangThe First School of Clinical Medicine, Lanzhou University Lanzhou 730000, Gansu, China.
Xiaohu WangThe First School of Clinical Medicine, Lanzhou University Lanzhou 730000, Gansu, China.
Qiuning ZhangThe First School of Clinical Medicine, Lanzhou University Lanzhou 730000, Gansu, China.
Yan MaThe First School of Clinical Medicine, Lanzhou University Lanzhou 730000, Gansu, China.
Zi WangDepartment of Oncology, Guizhou Provincial People's Hospital Guiyang 550002, China.
First Hospital of Lanzhou University · CNGansu Provincial Hospital · CNGuizhou Provincial People's Hospital · CNInstitute of Modern Physics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo investigate the roles of deleted in lymphocytic leukemia-2 (DLEU2) in the pathology of cervical cancer.

methodsDifferentially expressed long non-coding RNAs between cervical cancerous and para-cancerous tissues were examined in 26 clinical specimens by microarray analysis and quantitative real-time PCR. DLEU2 expression was correlated with clinical features in 108 patients with cervical cancer. The effects of DLEU2 on growth, proliferation, migration, and invasion were examined in cervical cancer cells.

resultsDLEU2 was correlated with lymphovascular invasion in patients with cervical cancer. DLEU2 overexpression inhibited cell proliferation, migration, and proliferation, and colony formation in cervical cancer cells.

conclusionDLEU2 is involved in the pathology of cervical cancer, and it may be a target for clinical therapy.

Indexed as

Cervical cancerdeleted in lymphocytic leukemia 2long non-coding RNA

Identifiers

PMID32922596
PMCPMC7476956
OpenAlexW3086301316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.