ReviewInflammation and regeneration2020
Development of tooth regenerative medicine strategies by controlling the number of teeth using targeted molecular therapy.
Review in Inflammation and regeneration, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Stem cell-driven biomedical technologies for tooth regeneration: engineering scaffolds, organoid models, and molecular targeted strategies.Stem cell research & therapy · 2026Review
- Dissecting the Genetic Contribution of Tooth Agenesis.International journal of molecular sciences · 2025Review
- The rising potential of tooth germ-derived stem cells and the future of oral rehabilitation.Journal of advanced periodontology & implant dentistry · 2025Article
- Comparative proteomic analysis of dental pulp from supernumerary and normal permanent teeth.Clinical oral investigations · 2024Article
- Clinical features of non-syndromic late developing supernumerary teeth: a sign of the third dentition?BMC oral health · 2024Article
- Advances in tooth agenesis and tooth regeneration.Regenerative therapy · 2023Review
- Tooth number abnormality: from bench to bedside.International journal of oral science · 2023Review
- Identification of potential key variants in mandibular premolar hypodontia through whole-exome sequencing.Frontiers in genetics · 2023Article
- Anti-USAG-1 therapy for tooth regeneration through enhanced BMP signaling.Science advances · 2021Article
- Spatiotemporal Changes in Transcriptome of Odontogenic and Non-odontogenic Regions in the Dental Arch ofFrontiers in cell and developmental biology · 2021Article
- Supernumerary teeth: A pictorial review and revised classification.Journal of oral biology and craniofacial researchReview
- Research algorithm for the detection of genetic patterns and phenotypic variety of non-syndromic dental agenesis.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieObservational
- Phenotypic heterogeneity of non-syndromic supernumerary teeth: genetic study.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Analysis of various genetically modified mice, with supernumerary teeth, has revealed the following two intrinsic molecular mechanisms that increase the number of teeth. One plausible explanation for supernumerary tooth formation is the rescue of tooth rudiments. Topical application of candidate molecules could lead to whole tooth formation under suitable conditions. Congenital tooth agenesis is caused by the cessation of tooth development due to the deletion of the causative gene and suppression of its function. The arrest of tooth development in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.