Evidence map›Paper›PMID 32922498›Full record

ArticleIranian journal of pharmaceutical research : IJPR2020

Antioxidant Activity and Hemocompatibility Study of Quercetin Loaded Plga Nanoparticles.

Serap Derman, Deniz Uzunoglu, Tayfun Acar, Tulin Arasoglu, Samet Ucak, V Cengiz Ozalp, Banu Mansuroglu

Abstract read
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Comparative evaluation of quercetin, rutin, and their nanoparticles: enhanced antimicrobial and antioxidant activities.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. In-Vitro Effect ofIranian journal of parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Serap DermanBioengineering Department, Chemical and Metallurgical Engineering Faculty, Yildiz Technical University, Esenler, Istanbul, Turkey.
Deniz UzunogluBioengineering Department, Chemical and Metallurgical Engineering Faculty, Yildiz Technical University, Esenler, Istanbul, Turkey.
Tayfun AcarBioengineering Department, Chemical and Metallurgical Engineering Faculty, Yildiz Technical University, Esenler, Istanbul, Turkey.
Tulin ArasogluMolecular Biology and Genetics Department, Science and Letters Faculty, Yıldız Technical University, Esenler, Istanbul, Turkey.
Samet UcakMedical Biology Department, Medicine Faculty, Altinbas University, Bakirkoy, Istanbul, Turkey.
V Cengiz OzalpBioengineering Department, Engineering and Architecture Faculty, Konya Food and Agriculture University, Meram, Konya, Turkey.
Banu MansurogluMolecular Biology and Genetics Department, Science and Letters Faculty, Yıldız Technical University, Esenler, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quercetin (QU) is an important flavonoid compound presenting lots of biological activities, but its application has been limited due to its low aqueous solubility and instability. In this study, conducted to improve these properties of the quercetin, quercetin-encapsulated PLGA nanoparticles were prepared, characterized, and evaluated for antioxidant and hemolytic activity. Nanoparticles were produced by single emulsion solvent evaporation method. Four different process parameters initial QU amount, PVA concentration, PVA volume, and initial PLGA amount were investigated to obtain the nanoparticles which have minimum particle size and maximum entrapment efficiency. Synthesized nanoparticles were evaluated for particle size, entrapment efficiency, and reaction yield. Additionally, antioxidant properties and

Indexed as

Antioxidant activityHemocompatibilityHemolytic activityPolymeric nanoparticleQuercetin

Identifiers

PMID32922498
PMCPMC7462503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.