Evidence map›Paper›PMID 32922389›Full record

ReviewFrontiers in immunology2020

Inducing Immunity Where It Matters: Orthotopic HPV Tumor Models and Therapeutic Vaccinations.

Samantha Zottnick, Alessa L Voß, Angelika B Riemer

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  9. Human HLA prolongs the host inflammatory response inFrontiers in cellular and infection microbiology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Samantha ZottnickImmunotherapy and Immunoprevention, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Alessa L VoßImmunotherapy and Immunoprevention, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Angelika B RiemerImmunotherapy and Immunoprevention, German Cancer Research Center (DKFZ), Heidelberg, Germany.
German Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anogenital and oropharyngeal cancers caused by human papillomavirus (HPV) infections account for 4.5% of all cancer cases worldwide. So far, only the initial infection with selected high-risk types can be prevented by prophylactic vaccination. Already existing persistent HPV infections, however, can currently only be treated by surgical removal of resulting lesions. Therapeutic HPV vaccination, promoting cell-based anti-HPV immunity, would be ideal to eliminate and protect against HPV-induced lesions and tumors. A multitude of vaccination approaches has been tested to date, many of which led to high amounts of HPV-specific T cells

Indexed as

AlphapapillomavirusAnimalsCancer VaccinesCD8-Positive T-LymphocytesCell Line, TumorHost-Pathogen InteractionsHumansImmunity, MucosalLymphocytes, Tumor-InfiltratingMice, TransgenicNeoplasms, ExperimentalPapillomavirus InfectionsPapillomavirus VaccinesVaccinationCancer VaccinesPapillomavirus VaccinesHPVMHC-humanized miceorthotopic tumor modelstherapeutic vaccinationtissue-resident T cells

Identifiers

PMID32922389
PMCPMC7457000
OpenAlexW3049552624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.